In 2012, New York City Mayor Michael Bloomberg proposed capping the size of sugary beverages that could be sold in the city’s restaurants, sporting and entertainment facilities and food carts. After a lawsuit and multiple appeals, the proposal died in June 2014, deemed an unconstitutional overreach. In dissecting the saga of the proposed soda cap, we highlight both the political perils of certain anti-obesity efforts and, more broadly, the challenges to public health when issues of consumer choice and the threat (...) of paternalism are involved. (shrink)

Advancements in fetal assessment and therapeutic intervention in medical practice and clinical research call for corresponding progress in regulatory and ethical guidance. In “A new ethical framewo...

We report on the deliberations of an interdisciplinary group of experts in science, law, and philosophy who convened to discuss novel ethical and policy challenges in stem cell research. In this report we discuss the ethical and policy implications of safety concerns in the transition from basic laboratory research to clinical applications of cell-based therapies derived from stem cells. Although many features of this transition from lab to clinic are common to other therapies, three aspects of stem cell biology pose (...) unique challenges. First, tension regarding the use of human embryos may complicate the scientific development of safe and effective cell lines. Second, because human stem cells were not developed in the laboratory until 1998, few safety questions relating to human applications have been addressed in animal research. Third, preclinical and clinical testing of biologic agents, particularly those as inherently complex as mammalian cells, present formidable challenges, such as the need to develop suitable standardized assays and the difficulty of selecting appropriate patient populations for early phase trials. We recommend that scientists, policy makers, and the public discuss these issues responsibly, and further, that a national advisory committee to oversee human trials of cell therapies be established. **NB we did not reccommend a NAC, we think it might be appropriate**. (shrink)

The scientific, ethical, and policy issues raised by research involving the engraftment of human neural stem cells into the brains of nonhuman primates are explored by an interdisciplinary working group in this Policy Forum. The authors consider the possibility that this research might alter the cognitive capacities of recipient great apes and monkeys, with potential significance for their moral status.

After witnessing extraordinary scientific and regulatory efforts to speed development of and access to new COVID-19 interventions, patients facing other serious diseases have begun to ask “where’s...

Patients have received experimental pharmaceuticals outside of clinical trials for decades. There are no industry-wide best practices, and many companies that have granted compassionate use, or ‘preapproval’, access to their investigational products have done so without fanfare and without divulging the process or grounds on which decisions were made. The number of compassionate use requests has increased over time. Driving the demand are new treatments for serious unmet medical needs; patient advocacy groups pressing for access to emerging treatments; internet platforms (...) enabling broad awareness of compelling cases or novel drugs and a lack of trust among some that the pharmaceutical industry and/or the FDA have patients’ best interests in mind. High-profile cases in the media have highlighted the gap between patient expectations for compassionate use and company utilisation of fair processes to adjudicate requests. With many pharmaceutical manufacturers, patient groups, healthcare providers and policy analysts unhappy with the inequities of the status quo, fairer and more ethical management of compassionate use requests was needed. This paper reports on a novel collaboration between a pharmaceutical company and an academic medical ethics department that led to the formation of the Compassionate Use Advisory Committee. Comprising medical experts, bioethicists and patient representatives, CompAC established an ethical framework for the allocation of a scarce investigational oncology agent to single patients requesting non-trial access. This is the first account of how the committee was formed and how it built an ethical framework and put it into practice. (shrink)

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

Deciding whether to grant an expanded access request for a child whose sibling is enrolled in a gene therapy trial involves a number of complex factors: considering the best interests of the child, the psychosocial and economic impact on the family, and the concerns and obligations of researchers. Despite the challenges in coming to a substantively fair outcome in cases of discordant eligibility, creating a procedurally fair decision-making process to adjudicate requests is essential.

Volume 19, Issue 6, June 2019, Page 22-25.

Documentary evidence has recently been discovered in the Archives at Petworth House, West Sussex, for the setting up of a laboratory in the House at the end of the eighteenth century. This paper gives details of those involved in the setting up of the laboratory, and of their other scientific and cultural interests. The accounts from the suppliers of the laboratory equipment are transcribed, and a brief description given of the many pieces of equipment from the laboratory that (...) still survive at Petworth House. (shrink)

In an oft-quoted letter, King James IV wrote to the Dominican Prior General that Scotland was "almost the most remote region in the world."1 Nevertheless, as scholarship of the past fifteen years has shown, later medieval Scotland played a central role in Latin Christendom.2 Perhaps most importantly for the current study, numerous religious orders were active in Scotland and had significant ties to the Continent.3 Many of the same questions pertaining to Continental houses also exist for Scotland. In particular, there (...) are many unanswered questions about the group known as the Franciscan third order. Sources indicate that there were a number of men and women known as... (shrink)

Traditional Franciscan history holds that Francis of Assisi founded an order of lay penitents, which was given both a rule and official approval by Pope Nicholas IV in 1289. In this accepted version of events, the 1289 rule was followed by houses of men and women until the sixteenth century, and only replaced when a desire for greater unity within the Franciscan third order led Leo X to issue a new rule in 1521.2 Despite not standing up to historical scrutiny, (...) studies of the third order seldom question this official narrative.3 Moreover, although the 1521 rule is generally mentioned, little attention is given to either its context or significance.4 When the historical circumstances of this new rule are .. (shrink)

The question of how the ‘border’ is conceived in international law, and how it shapes identity and peoples’ lives, remains largely unexplored in the international legal literature. This article seeks to contribute to our understanding of the meaning of the border in international law, and in the contemporary context, by drawing on the work of the philosopher and political theorist, Étienne Balibar, and by reflecting, in the light of his work, on the recent decision of the House of Lords (...) in R v Immigration Officer at Prague Airport. It is shown that international law's focus on the territorial border may render invisible other borders which are significant for subaltern groups, and thereby fail to address the manner in which borders affect lives and determine outcomes. Borders are not stable and ‘univocal’, but instead, ‘multiple’, shifting in meaning and function from group to group. They are also being ‘exported’ such that a person may experience a foreign border while still within the territory of their own country. In highlighting the multiplicity of borders, the article seeks to prompt further reflection on the articulation and application of norms of international law in a way that addresses the realities of the contemporary context. (shrink)

We conducted and analyzed qualitative interviews with 12 persons working on the Healthy Public Housing Initiative in Boston, Massachusetts in 2001. Our goal was to generate ideas and themes related to the ethics of the community-based participatory research in which they were engaged. Specifically, we wanted to see if we found themes that differed from conventional research that is based on an individualistic ethics. There were clearly distinct ethical issues raised with respect to projects and individuals who engage in community-based (...) collaborations. The differences that arose from the interviews were seeking equality between the partners, the need for the community partner to defend the community, dealing with unflattering data, meeting community expectations and producing tangible benefits to the community. (shrink)

International political economy identifies declining nominal interest rates, securitization, and financial liberalization as drivers of rising housing prices. Despite witnessing these common credit shocks, however, developed economies experienced divergent trends in housing inflation since the 1980s. We offer a comparative political economy explanation of variation in house prices, arguing that by restraining household incomes, wage-setting institutions can blunt financial liberalization’s inflationary impact on housing markets. Employing quantitative analysis and a comparative study of Ireland and the Netherlands, we uncover two (...) findings. First, countries where political coalitions in the export sector held veto powers over those in the nontraded sector in national wage setting realized lower housing inflation. Second, the impact of sectoral coalitions on housing prices in OECD countries is similar to that of financial variables. Our results suggest that the organization of labor politics continues to play an important role in mitigating the destabilizing effects of global finance on developed economies. (shrink)

Insofar as the material residues of interest to archaeologists are cultural and, as such, have specifically symbolic significance, it is argued that archaeology must employ some form of structuralist analysis (i.e. as specifically concerned with this aspect of the material). Wylie examines the prevalent notion that such analysis is inevitably 'unscientific' because it deals with a dimension of material culture which is inaccessible of any direct, empirical investigation, and argues that this rests on an entrenched misconception of science; it assumes (...) that scientific enquiry must be restricted to observables. It is clear, as realist critics of this view have argued, that scientific (explanatory) understanding depends fundamentally on theoretical extensions beyond observables; extensions which bring into view underlying and inaccessible causal structures or mechanisms responsible for the mani- fest phenomena through a procedure of analogical model construc- tion. In consideration of realist models of these procedures and of the potential of linguistic modes of analysis for archaeology, it is pro- posed that archaeologists might (and, in fact, often do) effectively grasp the symbolic, structural order of surviving material culture through analysis governed by a rigorous and controlled use of ethno- graphic analogy. It is claimed, moreover, that the archaeological record can provide empirical bases for evaluating these theoretical constructs if a procedure of recursive and systematic testing is adopted in research, but the standard hypothetico-deductive model is seriously flawed as an account of an ideal for this procedure. Glassie's analysis of Middle Virginian folk housing is an example of research along these lines which illustrates the potential for a rigorous structuralist alternative. (shrink)

John Fischer and Mark Ravizza defend in this book a painstakingly constructed analysis of what they take to be a core condition of moral responsibility: the notion of guidance control. The volume usefully collects in one place ideas and arguments the authors have previously published in singly or jointly authored works on this and related topics, as well as various refinements to those views and some suggestive discussions that aim to show how their account of guidance control might fit into (...) a more comprehensive account of moral responsibility. (shrink)

The thought that empathy plays an important role in moral motivation is almost a platitude of contemporary folk psychology. Parallel themes were mooted in German moral philosophy and aesthetics in the 1700s, and versions of the empathy construct remained prominent in continental accounts of moral motivation through the nineteenth century and early twentieth centuries. This chapter elucidates the Empathic Motivation Hypothesis (EMH) and sets out some of the conceptual and empirical challenges it faces. It distinguishes empathic concern from other dimensions (...) of empathy (e.g., resonance, attunement, distress, and non-empathic concern) and examines the merits of EMH as a developmental thesis, focusing on evidence from psychopathology and attachment theory. (shrink)

My project is to explain why the question ‘How does it feel to be a white problem?’ cannot be answered in the fluttering grammar of white talk. The whiteness of white talk lies not only in its having emerged from white mouths, but also in its evasiveness—in its attempt to suppress fear and anxiety, and its consequential [if unintended] reinscription and legitimation of racist oppression. I White talk is designed, indeed scripted, for the purposes of evading, rejecting, and remaining ignorant (...) about the injustices that flow from whiteness and its attendant privileges. I want to suggest a new point of entry—a way to flip the script, so to speak. -/- I begin with some observations about the basic advantages and disadvantages of using white talk as a route into the white problem. My account develops an expanded version of Alice MacIntyre’s definition of white talk that is attentive to the racialized bodily scripts that accompany white talk. I argue that white talk persists because it has an enduring and powerful moral, ontological, and epistemic pay off for white folks. I explore each payoff with an eye towards clarifying how white talk functions to maintain the illusion that we are invulnerable beings. Next, I pause to reply to the popular objection that this particular critique of white talk silences white people in conversations on race. If we cannot address the question ‘how does it feel to be a white problem’ in the fluttering grammar of white talk, then how shall we begin? In closing, I suggest that we might reduce fluttering by replacing white talk with a discourse of vulnerability, where vulnerability is defined not as weakness, but as a condition for potential. I offer some brief guidelines for how we might start this conversation. (shrink)

This short article argues that an adequate response to the implications for governance raised by ‘Big Data’ requires much more attention to agency and reflexivity than theories of ‘algorithmic power’ have so far allowed. It develops this through two contrasting examples: the sociological study of social actors used of analytics to meet their own social ends and the study of actors’ attempts to build an economy of information more open to civic intervention than the existing one. The article concludes with (...) a consideration of the broader norms that might contextualise these empirical studies, and proposes that they can be understood in terms of the notion of voice, although the practical implementation of voice as a norm means that voice must sometimes be considered via the notion of transparency. (shrink)

It is no accident that white privilege designed to be both be invisible and weightless to white people. Alison Bailey’s “On White Privilege and Anesthesia: Why Does Peggy McIntosh’s Knapsack Feel Weightless?” extends a weighty invitation white readers to complete the unpacking task McIntosh (1988) began when she compared white privilege to an “invisible and weightless knapsack.” McIntosh focuses primarily making white privilege visible to white people. Bailey’s project continues the conversation by extending a ‘weighty invitation’ to white readers (...) to explore why the metaphorical knapsack, despite the weight of its contents, feels weightless. Here’s the short answer. The knapsack only feels weightless because white people have become anesthetized us to our own brokenness. We are more comfortable considering what white privilege does for us than what it does to us. People of color feel the weight of whiteness every day. The weighty invitation invites white readers to become sensitive to our own insensitivity. To do this Bailey (1) explores white resistance to unpacking the weight; (2) people of color’s testimonies to the daily impact of the weight on their bodies; and (3) how the anesthesia of white privilege distorts our humanity. The article concludes with a McIntosh style list of that the anesthesia of privilege distorts white people’s humanity. (shrink)

Causes always seem to come prior to their effects. What might explain this asymmetry? Causation's temporal asymmetry isn't straightforwardly due to a temporal asymmetry in the laws of nature—the laws are, by and large, temporally symmetric. Nor does the asymmetry appear due to an asymmetry in time itself. This Element examines recent empirical attempts to explain the temporal asymmetry of causation: statistical mechanical accounts, agency accounts and fork asymmetry accounts. None of these accounts are complete yet and a full explanation (...) of the temporal asymmetry of causation will likely require contributions from all three programs. (shrink)

The book offers an original defence of a new materialist thesis that focuses on the biological core of humans to develop a theory of human rights.

This book explores the meaning and practice of corporeal ethics in organized life. Corporeal ethics originates from an emergent, embodied and affective experience with others that precedes and exceeds those rational schemes that seek to regulate it. Pullen and Rhodes show how corporeal ethics is fundamentally based in embodied affect, yet practically materialized in ethico-political acts of positive resistance and networked solidarity. Considering ethics in this way turns our attention to how people's conduct and interactions might be ethically informed in (...) the context of, and in resistance to, the masculine rationality of dominating organizational power relations in which they find themselves. Pullen and Rhodes outline the ways in which ethically grounded resistance and critique can and do challenge self-interested organizational power and privilege. They account for how corporeal ethics serves to destabilize the ways that organizations reproduce practices that negate difference and result in oppression, discrimination, and inequality. The book is suitable for students, scholars and citizens who want to learn more about the radical possibilities of how political actions arising from corporeal ethics can strive for equality and justice. (shrink)

Vladimir Putin's image functions as a political talisman far outside of the borders of his own country. By studying material objects, fan fiction and digital media, this book traces the satirical uses of Putin's public persona, notably how he stands as a foil for other world leaders. It argues that the internet is crucial to the creation of contemporary Putin memorabilia and that these items show a continued political engagement by young people, even as some political scientists and media experts (...) decry what they see as the opposite. The book further addresses the ways in which explicit sexual references about government officials are being used as everyday political commentary in the United States. Turning a critical eye to Putin kitsch shows how the number of such references skyrocketed during the 2016 US Presidential election campaign, and suggests that the phenomenon is likely to still be important when Americans next return to the polls. Finally, the internet makes possible a totally new kind of kitsch--the virtual kind. An examination of how the Russian president's image circulates via memes and parodies, as well as through apps and games, suggests that political culture has become increasingly participatory in the last decade. (shrink)

This paper problematises the ways women’s leadership has been understood in relation to male leadership rather than on its own terms. Focusing specifically on ethical leadership, we challenge and politicise the symbolic status of women in leadership by considering the practice of New Zealand Prime Minister Jacinda Ardern. In so doing, we demonstrate how leadership ethics based on feminised ideals such as care and empathy are problematic in their typecasting of women as being simply the other to men. We apply (...) different strategies of mimesis for developing feminist leadership ethics that does not derive from the masculine. This offers a radical vision for leadership that liberates the feminine and women’s subjectivities from the masculine order. It also offers a practical project for changing women’s working lives through relationality, intercorporeality, collective agency and ethical openness with the desire for fundamental political transformation in the ways in which women can lead. (shrink)

One of the most actively discussed aspects of Keynes's thought during the last decade has been his concern with uncertainty and probability theory. As the concerns of current macroeconomic theorists have turned increasingly to the effects of expectations and uncertainty, interest has grown in the fact that Keynes was the author of A Treatise on Probability and that uncertainty plays a prominent role in Chapter 12 of The General Theory as well as in three 1937 papers in which he summarized (...) The General Theory's main point. Not surprisingly, though, there has been very little agreement in this recent discussion about exactly what the significance of Keynes's early work in probability was to his later work as an economist, or about what the roles of uncertainty and expectations are in The General Theory. (shrink)

ABSTRACT This article suggests that Asian American rhetorics of sound destabilize representational politics by complicating the racialization of sonic difference. The author investigates the relationship between notions of Asian American citizenship and not-Blackness in vocal performance. By attending to sonic rhetorics through Awkwafina’s blaccent controversy, the article explores the condition of epistemic violence that position Asian American voices as “unhearable.”.

This is a long-overdue biography of the Huxleys: the Victorian natural historian T.H. Huxley ("Darwin's Bulldog") and his grandson, the scientist, conservationist, and zoologist Julian Huxley. Both T.H. and Julian suffered from depression, thinking and writing about the condition and genetic inheritance in highly curious ways. And between them, they communicated to the world the great modern story of the theory of evolution by natural selection. Because the grandson modeled himself so self-consciously on the grandfather, celebrated historian Alison Bashford (...) writes seamlessly about these omnivorous intellects together, almost as if they were one very long-lived man whose vital dates bookended the colossal shifts in world history from the age of sail to the Space Age, and from colonial wars to world wars to the cold war. The myriad questions that the Huxleys grappled with make them the perfect dynasty-companions for time travel over the age of evolution: What is the nature of time and how old is the Earth itself? What is the connection between human history and natural history? How are humans animals and how are we not? What is the deep past and the distant future of humankind? Can and should we actively seek to improve future generations? What might the planet look like 10,000 years hence? This momentous biography traces the problems and wonders of the modern world that the Huxleys themselves raised, postured, and pondered over lives that spanned the age of evolution. (shrink)

Many women wrote philosophy in nineteenth-century Britain, and they wrote across the full range of philosophical topics. Yet these important women thinkers have been left out of the philosophical canon and many of them are barely known today. The aim of this book is to put them back on the map. It introduces twelve women philosophers - Mary Shepherd, Harriet Martineau, Ada Lovelace, George Eliot, Frances Power Cobbe, Helena Blavatsky, Julia Wedgwood, Victoria Welby, Arabella Buckley, Annie Besant, Vernon Lee, and (...) Constance Naden. Alison Stone looks at their views on naturalism, philosophy of mind, evolution, morality and religion, and progress in history. She shows how these women interacted and developed their philosophical views in conversation with one another, not only with their male contemporaries. The rich print and periodical culture of the period enabled these women to publish philosophy in forms accessible to a general readership, despite the restrictions women faced, such as having limited or no access to university education. Stone explains how these women became excluded from the history of philosophy because there was a cultural shift at the end of the nineteenth century towards specialised forms of philosophical writing, which depended on academic credentials that were still largely unavailable to women. (shrink)

As Spinoza's near‐total omission from the history of physics reflects, Spinoza never produced a physics in this narrow sense: a careful and systematic investigation of bodies, forces, and their motions of the kind found in Descartes, Regius, or Huygens. Spinoza did have things to say about extension, motion, and the causal interactions of bodies. Understanding Spinoza's physics requires reckoning with his responses to Descartes. Like Descartes, Spinoza thinks that all and only bodies share an attribute, the attribute of Extension. Spinoza's (...) commitment to the “attribute‐neutrality” of some causal facts is reflected in his physics. Attribute‐neutrality can also make sense of some changes in the DPP. Physics investigates the nature and properties of bodies, so for Spinoza as for Descartes, it will involve an analysis of the attribute of Extension. Spinoza never drew out the detailed physical implications of his metaphysics of bodies. (shrink)

This chapter contains sections titled: Saddle Up and Swallow Your Pride The Made Hunter: Product and Agent Horses and Humans: A Foxhunting Partnership Foxhunting Resonances Notes.

Even without Alzheimer's or dementia, most of us are prone to “ordinary forgetting”. The Good Place and careful philosophical reflection can help us think through memory loss, relationships, and making a place for each other as we live through the human condition. Throughout The Good Place, Chidi and Eleanor help each other develop and sustain their moral selves as well as their relationship. Stories are fundamental to our sense of self, right and wrong, and the kind of people we are. (...) To understand memory as a construction, we must understand the three stages of individual memory: encoding, storage, and retrieval. How we scaffold each other's identities and how we hold space for each other in the real world are ethical issues that have everything to do with memory and the stories we tell ourselves and each other. The Good Place can help us grapple with this. (shrink)

The book offers an original defence of a new materialist thesis that focuses on the biological core of humans to develop a theory of human rights.

Women Activating Agency in Academia seeks to create and expand safe spaces for scholarly, professional and personal stories and assemblages of agency. It provides readers with the opportunity to connect with the strategies women are using to navigate academe and the core values, linked to trust, relationship, wellbeing and ethics of care, they live by. The collection offers the stories of women academics from around the globe and across disciplines and showcases their efforts to meaningfully listen and converse in order (...) to resist self-audit and diminished identities. Reflections come from a range of responsive, personal and aesthetic techniques, including writing groups, guided autobiography, auto-ethnography, collective activism and slow scholarship. Chapters engage with themes and ideas such as agency, neoliberalism, ontological security, androcentricity, identity and collegial support, which manifest in unique ways for female academics. The focus in this volume is what really matters to women in the academy, as they share their efforts to 'be' themselves in their work, to 'care for themselves and others' and to 'count what isn't counted'. It aims to prove how collaborative storytelling and discussion can empower female academics to preserve and achieve these ambitions. (shrink)

Initiatives which offer support to primary care practitioners interested in research have become widespread in the UK. There has been little debate, however, about the ethical issues involved in such interactions with practitioners. Established codes of practice and analyses of the institutional and strategic contexts have been used to inform this discussion. The paper concludes with a recommendation that more explicit quasi-contractual relationships should be negotiated between those offering and those seeking help.

This article is inspired by theoretical developments within the social sciences that focus on the materiality of everyday objects and processes. Based on ethnographic research in the city of Carrara, in central Italy, the article discusses the experiences of both quarry workers and sculptors who work with marble. Through an exploration of one of the ‘qualisigns’ of marble — veining — the article draws attention to the material life of marble in the artistic imagination of sculptors and why materiality might (...) matter in social analysis. (shrink)

This is an easy to use, theme-based resource book for Philosophy for Children (P4C) practitioners in primary school settings. It covers 10 popular themes which include many current affair issues and enduring curriculum themes such as artificial intelligence, biodiversity, resilience, and waste. Each theme provides planning for every subject and links to the relevant English national curriculum expectations. Offering ideas for a year's worth of work, it can be dipped into for inspiration or used for step-by-step sessions. There are links (...) to video-clips, websites, and stories that teachers and practitioners can use to base their concept exploration and enquires on. Presenting a range of philosophical ideas, activities and resources, this book is essential for all primary P4C facilitators excited by embedding and exploring philosophy across the curriculum. (shrink)