Abstract The only biologically respectable notion of human nature is an extremely permissive one that names the reliable dispositions of the human species as a whole. This conception offers no ethical guidance in debates over enhancement, and indeed it has the result that alterations to human nature have been commonplace in the history of our species. Aristotelian conceptions of species natures, which are currently fashionable in meta-ethics and applied ethics, have no basis in biological fact. Moreover, because our folk psychology (...) finds this misleading Aristotelian conception highly tempting, we are in fact better off if we refrain from mentioning human nature altogether in debates over enhancement. Content Type Journal Article Category Special Issue Pages 1-16 DOI 10.1007/s13347-012-0063-x Authors Tim Lewens, Department of History and Philosophy of Science, University of Cambridge, Free School Lane, Cambridge, CB2 3RH UK Journal Philosophy & Technology Online ISSN 2210-5441 Print ISSN 2210-5433. (shrink)

A philosopher of science examines the biggest ethical and moral issues in science today, and explains why they matter for all of us--scientist and layman alike.

This chapter contains sections titled: Contemporary Naturalism The Virtues of Naturalism Naturalistic Excess: The Pessimistic Induction Naturalistic Excess: Causation Naturalistic Excess: “Preaching to Scientists” Naturalistic Excess: Experimental Philosophy Eclectic Naturalism References.

An argument against the view that natural norms are constituted out of some form of historical success.

Tim Lewens aims to understand what it means to take an evolutionary approach to cultural change, and why it is that these approaches are sometimes treated with suspicion. While making a case for the value of evolutionary thinking for students of culture, he shows why the concerns of sceptics should not dismissed as mere prejudice, confusion, or ignorance. Indeed, confusions about what evolutionary approaches entail are propagated by their proponents, as well as by their detractors. By taking seriously the (...) problems faced by these approaches to culture, he shows how such approaches can be better formulated, where their most significant limitations lie, and how the tools of cultural evolutionary thinking might become more widely accepted. (shrink)

Preface ix 1 Meaning and the Means to an Understanding of Ends 2 Why Is an Eye? 21 3 Adaptationism and Engineering 39 4 On Five "-Isms" 67 5 Function, Selection, and Explanation 87 6 Deflating Function 119 7 Artifacts and Organisms 139 References 167 Index 177.

Much recent work on the ethics of new biomedical technologies is committed to hidden, contestable views about the nature of biological reality. This selection of essays by Tim Lewens explores and scrutinises these biological foundations, and includes work on human enhancement, synthetic biology, and justice in healthcare decision-making.

Godfrey-Smith ( 2001 ) has distinguished three types of adaptationism. This article builds on his analysis, and revises it in places, by distinguishing seven varieties of adaptationism. This taxonomy allows us to clarify what is at stake in debates over adaptationism, and it also helps to cement the importance of Gould and Lewontin’s ‘Spandrels’ essay. Some adaptationists have suggested that their essay does not offer any coherent alternative to the adaptationist programme: it consists only in an exhortation to test adaptationist (...) hypotheses more thoroughly than was usual in the 1970s. Here it is argued that the ‘Spandrels’ paper points towards a genuinely non-adaptationist methodology implicit in much evolutionary developmental biology. This conclusion helps to expose the links between older debates over adaptationism and more recent questions about the property of evolvability. (shrink)

In this invaluable book, Tim Lewens shows in a clear and accessible manner how important Darwin is for philosophy and how his work has shaped and challenged the very nature of the subject. Beginning with an overview of Darwin’s life and work, the subsequent chapters discuss the full range of fundamental philosophical topics from a Darwinian perspective. These include natural selection; the origin and nature of species; the role of evidence in scientific enquiry; the theory of Intelligent Design; evolutionary (...) approaches to the human mind; the implications of Darwin’s work for ethics and epistemology; and the question of how social and political thought needs to be updated in the light of a Darwinian understanding of human nature. A concluding chapter assesses the philosophical legacy of Darwin’s thought. _Darwin_ is essential reading for anyone in the humanities, social sciences and sciences seeking a philosophical introduction to Darwin, or anyone simply seeking a philosophical companion to Darwin’s own writings. (shrink)

Sperm, eggs and embryos are made up of more than genes, and there are indications that changes to non‐genetic structures in these elements of the germline can also be inherited. It is, therefore, a mistake to treat phrases like ‘germline inheritance’ and ‘genetic inheritance’ as simple synonyms, and bioethical discussion should expand its focus beyond alterations to the genome when considering the ethics of germline modification. Moreover, additional research on non‐genetic inheritance draws attention to a variety of means whereby differences (...) can be inherited in offspring generations that do not rely on differences in germline structures. Research on these diverse forms of inheritance challenges the notion that there is some special form of ethical concern that falls on germline interventions in general, and on interventions to the nuclear genome within the germline in particular. (shrink)

Elliott Sober and his defenders think of selection, drift, mutation, and migration as distinct evolutionary forces. This paper exposes an ambiguity in Sober's account of the force of selection: sometimes he appears to equate the force of selection with variation in fitness, sometimes with ‘selection for properties’. Sober's own account of fitness as a property analogous to life-expectancy shows how the two conceptions come apart. Cases where there is selection against variance in offspring number also show that selection and drift (...) cannot be distinguished in the way Sober hopes for. These issues have significance beyond the parochial matter of the coherence of Sober's system. There is no good principled answer to the question of which features of a population should count among the contributors to fitness. This means there is no non-arbitrary account of the nature of selection. (shrink)

How can we determine an acceptable level of risk? Should these decisions be made by experts, or by the people they affect? How should safety and security be balanced against other goods, such as liberty? This is the first collection to examine the philosophical dimensions of these pressing practical problems. Leading scholars exploring the full range of philosophical implications of risk, including: risk and ethics risk and rationality risk and scientific expertise risk and lay knowledge the objectivity of risk assessment (...) risk and the precautionary principle risk and terror. With contributions from Carl F. Cranor, Sven Ove Hansson, Martin Kusch, Tim Lewens, D.H. Mellor, Adam Morton, Stephen Perry, Martin Peterson, Alan Ryan, Per Sandin, Cass R. Sunstein and Jonathan Wolff; this collection is essential reading, not only for philosophers and researchers in legal, economic and environmental studies, but for those seeking to gain a better understanding of the decisions we must make as concerned citizens. (shrink)

Is human nature something that the natural and social sciences aim to describe, or is it a pernicious fiction? What role, if any, does ”human nature’ play in directing and informing scientific work? Can we talk about human nature without invoking---either implicitly or explicitly---a contrast with human culture? It might be tempting to think that the respectability of ”human nature’ is an issue that divides natural and social scientists along disciplinary boundaries, but the truth is more complex. The contributors to (...) this collection take very different stances with regard to the idea of human nature. They come from the fields of psychology, the philosophy of science, social and biological anthropology, evolutionary theory, and the study of animal cognition. Some of them are ”human nature’ enthusiasts, some are sceptics, and some say that human nature is a concept with many faces, each of which plays a role in its own investigative niche. Some want to eliminate the notion altogether, some think it unproblematic, others want to retain it with reforming modifications. Some say that human nature is a target for investigation that the human sciences cannot do without, others argue that the term does far more harm than good. The diverse perspectives articulated in this book help to explain why we disagree about human nature, and what, if anything, might resolve that disagreement. Introduction Tim Lewens 1 Doubling Down on the Nomological Notion of Human Nature Edouard Machery 2 Trait Bin and Trait Cluster Accounts of Human Nature Grant Ramsey 3 A Developmental Systems Account of Human Nature Karola Stotz and Paul Griffiths 4 Human Nature, Natural Pedagogy, and Evolutionary Causal Essentialism Cecilia Heyes 5 Human Nature John Dupré 6 Sceptical Reflections on Human Nature Kim Sterelny 7 The Social Construction of Human Nature Kevin N. Laland and Gillian R. Brown 8 The Use and Non-Use of the Human Nature Concept by Evolutionary Biologists Peter J. Richerson 9 Human Ontogenies as Historical Processes Christina Toren 10 Divide and Conquer Maria Kronfeldner. (shrink)

Synthetic biology is often described as a project that applies rational design methods to the organic world. Although humans have influenced organic lineages in many ways, it is nonetheless reasonable to place synthetic biology towards one end of a continuum between purely ‘blind’ processes of organic modification at one extreme, and wholly rational, design-led processes at the other. An example from evolutionary electronics illustrates some of the constraints imposed by the rational design methodology itself. These constraints reinforce the limitations of (...) the synthetic biology ideal, limitations that are often freely acknowledged by synthetic biology’s own practitioners. The synthetic biology methodology reflects a series of constraints imposed on finite human designers who wish, as far as is practicable, to communicate with each other and to intervene in nature in reasonably targeted and well-understood ways. This is better understood as indicative of an underlying awareness of human limitations, rather than as expressive of an objectionable impulse to mastery over nature. (shrink)

argues that when reproduction is sexual, natural selection can explain why individual organisms possess the traits they do. In stating his argument Matthen makes use of a conception of individual organisms as receptacles for collections of genes—a conception that cannot do the work Matthen requires of it. Either these receptacles are abstract objects, such as bare possibilities for organisms, or they are concrete. The first reading is too weak, since it allows selection to explain individual traits in both sexual and (...) asexual contexts. The only concrete entities we might think of as receptacles for collections of genes are male or female gametes. It is true that in the sexual context selection explains why an individual gamete combines with a second gamete of one type rather than another; however, this is not to say that selection explains why an individual organism has the traits it does. (shrink)

What, if anything, is wrong with typological thinking? The question is important, for some evolutionary developmental biologists appear to espouse a form of typology. I isolate four allegations that have been brought against it. They include the claim that typological thinking is mystical; the claim that typological thinking is at odds with the fact of evolution; the claim that typological thinking is committed to an objectionable metaphysical view, which Elliott Sober calls the ‘natural state model’; and finally the view (endorsed (...) by Ron Amundson and Günter Wagner) that typological thinking—and specifically evolutionary developmental biology’s typological thinking—is committed to a peculiar form of causation that does not fit neatly into the causal models endorsed by population genetics. I argue that, properly understood, the typological thinking of evolutionary developmental biology does not run into any of these problems. *Received April 2008; revised August 2009. †To contact the author, please write to: Department of History and Philosophy of Science, University of Cambridge, Free School Lane, CB2 3RH Cambridge, United Kingdom; e‐mail: [email protected]. (shrink)

The four tenets of the Strong Program are compatible with a scientific realism founded on an externalist epistemology. Such an epistemology allows that appropriate norms of rationality may differ from time to time, and from community to community, and thereby enables the realist to embrace strong forms of the ‘symmetry principle’. It also suggests a fruitful collaborative research program in externalist social epistemology. Some of what the Edinburgh School says about truth can also be accepted. But the realist should reject (...) the School's argument for the claim that there is no distinction between being rational and being locally accepted as rational, which seems to rest on a kind of epistemological internalism. Introducing the Strong Program Realism and the four tenets A stronger reading of symmetry Conflict and cooperation A note on discovery and justification Relativism and realism Truth Points of contention: the restriction of explanatory contrasts Points of contention: standards of rationality. (shrink)

Michael and has argued that species have intrinsic essences. This paper rebuts Devitt’s arguments, but in so doing it shores up the anti-essentialist consensus in two ways that have more general interest. First, species membership can be explanatory even when species have no essences; that is, Tamsin’s membership of the tiger species can explain her stripyness, without this committing us to any further claim about essential properties of tigers. Second, even the views of species that appear most congenial to essentialism—namely (...) phenetic and genotypic cluster accounts—do not entail strong forms of intrinsic essentialism. (shrink)

The UK-based deliberations that led up to the legalisation of two new ‘mitochondrial donation’ techniques in 2015, and which continued after that time as regulatory details were determined, featured a division of advisory labour that is common when decisions are made about new technologies. An expert panel was convened by the Human Fertilisation and Embryology Authority, charged with assessing the scientific and technical aspects of these techniques. Meanwhile, the Nuffield Council on Bioethics addressed the ethical issues. While this division of (...) labour was undertaken in the name of thoroughness, I argue here that it can have the unintended consequence that hybrid questions that simultaneously involve ethical and technical aspects—especially questions about where to set evidential thresholds for the acceptance of new technology—do not receive enough attention. (shrink)

The UK-based deliberations that led up to the legalisation of two new ‘mitochondrial donation’ techniques in 2015, and which continued after that time as regulatory details were determined, featured a division of advisory labour that is common when decisions are made about new technologies. An expert panel was convened by the Human Fertilisation and Embryology Authority (HFEA), charged with assessing the scientific and technical aspects of these techniques. Meanwhile, the Nuffield Council on Bioethics addressed the ethical issues. While this division (...) of labour was undertaken in the name of thoroughness, I argue here that it can have the unintended consequence that hybrid questions that simultaneously involve ethical and technical aspects—especially questions about where to set evidential thresholds for the acceptance of new technology—do not receive enough attention. (shrink)

This paper examines the neo-Aristotelian account of species natures as ‘life-forms’, which we owe to Philippa Foot, Michael Thompson and their defenders. I begin by developing two problems for their view: a problem of underdetermination and a problem generated by psychological work on ‘folk essentialism’. I move on to consider their important transcendental argument, which suggests that claims about life-forms are presupposed by all efforts to describe the organic world. In response, I sketch a neo-Kantian projectivist position, which agrees that (...) life-forms are presupposed in these contexts, while denying that such life-forms are real. This position makes a better sense of the phenomena cited in support of the neo-Aristotelian view, while avoiding the problems raised for that view in the first half of this paper. (shrink)

The rights and wrongs of adaptationism areoften discussed by appeal to what I call theartefact model. Anti-adaptationistscomplain that the use of optimality modelling,reverse engineering and other techniques areindicative of a mistaken and outmoded beliefthat organisms are like well-designedartefacts. Adaptationists (e.g. Dennett 1995)respond with the assertion that viewingorganisms as though they were well designed isa fruitful, perhaps necessary research strategyin evolutionary biology. Anti-adaptationistsare right when they say that techniques likereverse engineering are liable to mislead. This fact does not undermine the artefact (...) modelprecisely because the same techniques misleadus for the same reasons when they are appliedunreflectively to artefacts. Thoseadaptationists who hold only that it isworthwhile to investigate organisms as thoughthey were artefacts and thoseanti-adaptationists who criticise simplisticdesign models have far more in common than thelabels attached to their positions mightsuggest. (shrink)

Few discussions of the ethics of mitochondrial ‘replacement’ techniques have drawn significant ethical distinctions between the two approaches now legal in the U.K. However, Anthony Wrigley, Stephen Wilkinson and John Appleby have together argued that under some circumstances pronuclear transfer (PNT) may be in better ethical standing than maternal spindle transfer (MST). They base their conclusion on what they allege to be different implications of the techniques with respect to non‐identity considerations, which they ground on a version of origin essentialism. (...) I raise a series of problems for their argument, which have cautionary implications for invocations of origin essentialism that go beyond specialized debates regarding MST and PNT. I argue that (i) origin essentialism is a fragile foundation for non‐identity considerations; (ii) gametic essentialism, which Wrigley et al. believe licenses their claims, is more questionable than origin essentialism; (iii) gametic essentialism does not straightforwardly justify their conclusion; and (iv) their conclusion in fact relies on an especially dubious position that we can call chromosomal origin essentialism. No good reasons have yet been supplied to distinguish PNT from MST on ethical grounds, and one should be wary of basing claims with practical impact on fragile foundations relating to origin essentialism. (shrink)

The varying demands of justice are often thought to depend on a distinction between natural and social inequalities, but making this distinction has been little discussed, and it has been dismissed by philosophers of biology. It cannot be established by a simple causal criterion, nor by use of the analysis of variance, nor by distinguishing the innate from the acquired. Whether an inequality can be socially controlled provides the most plausible criterion, so ‘natural’ and ‘social’ are misleading labels for types (...) of inequality. The analysis of these depends, besides, on how fine‐grained the descriptions are; so it is implausible to think that the natural/social distinction, when drawn in terms of social control, is relevant to theories of justice. (shrink)

A small minority of biologists, psychologists and philosophers have recently tried to show, in various ways, that evolutionary psychology is of relevance to politics and to policy makers. Two widely accepted arguments still suffice (with only a little tweaking) to dismiss such attempts to forge a link between evolution and policy. The first denies the link between adaptation and fixity, the second denies that ‘adaptive thinking’ is of strong heuristic benefit. Finally, the silence of many evolutionary explanations with respect to (...) developmental mechanisms should also make us suspicious of the relevance of evolutionary psychology to matters of policy. (shrink)

The pheneticist philosophy holds that biological taxa are clusters of entities united by a form of all-things-considered resemblance. This view of taxonomy has come in for almost universal criticism from philosophers, and has received little praise from biologists, over the past 30 years or so. This article defends a modest pheneticism, understood as part of a pluralist view of taxonomy. First, phenetic approaches to taxonomy are alive and well in biological practice, especially in the areas of microbiology and botany. Second, (...) the pheneticist notion of overall similarity is defensible, and is implicitly endorsed even by those (such as Quine) usually implicated in attacks on similarity. Third, there are limited biological domains within which pheneticism’s conception of species as kinds (rather than heterogeneous individuals) remains applicable. (shrink)

Alex Mesoudi’s book shows cultural evolution to be a mature field, which has already illuminated many instances of cultural change. Mesoudi’s presentation of the discipline nonetheless invites three objections. First, the culture concept it makes use of is not clearly defined; second, Mesoudi’s historical argument which looks back to the modern synthesis in order to predict an analogous synthesis in the social sciences is flawed; third, Mesoudi’s understanding of the positions held by leading figures within social science is shaky.

In the title chapter of Did Darwin Write the Origin Backwards?, Sober argues for an asymmetry between facts about genealogy and facts about natural selection, which has the result that evidentially Darwin's book is the wrong way round. Here I make three points about Sober's argument in that chapter. First, it is not clear that Darwin employs what Sober calls 'tree thinking' as frequently as Sober himself suggests. Second, I argue that Darwin's reason for structuring the Origin as he did (...) can be understood if we think of the Origin's argument as an inference to the best explanation. Third, I show circumstances where, even if selection is the only important evolutionary force, we would still be able to infer common ancestry. (shrink)

The varying demands of justice are often thought to depend on a distinction between natural and social inequalities, but making this distinction has been little discussed, and it has been dismissed by philosophers of biology. It cannot be established by a simple causal criterion, nor by use of the analysis of variance, nor by distinguishing the innate from the acquired. Whether an inequality can be socially controlled provides the most plausible criterion, so 'natural' and 'social' are misleading labels for types (...) of inequality. The analysis of these depends, besides, on how fine-grained the descriptions are; so it is implausible to think that the natural/social distinction, when drawn in terms of social control, is relevant to theories of justice. (shrink)

Buchanan and Powell’s book is a valuable contribution to our understanding of the evolution of morality. I suggest that they exaggerate the degree to which their view of the evolution of moral progress is committed to a form of moral realism. I also suggest that Darwin’s own approach to the evolution of the moral sense shares more with their view than they may realise. Finally I point to some tensions in their invocation of the concept of the Environment of Evolutionary (...) Adaptedness (EEA). (shrink)

Philosophers have nothing to lose, and much to gain, by paying close attention to developments in the natural sciences. This insight amounts to a case for a tempered, eclectic naturalism. But the case for naturalism is often overstated. We should not overestimate the heuristic benefits of close attention to scientists’ claims, nor should we give up on traditional “armchair” philosophical methods. We should not draw solely on the natural sciences (at the expense of the humanities) when seeking to enrich and (...) discipline our philosophical theorising. Finally, philosophers should not shy away from criticising some scientists’ claims, at the same time as they learn from others. (shrink)

Peter Godfrey-Smith’s introduction to the philosophy of biology is excellent. This review questions one implication of his book, namely that Darwin’s case for the efficacy of natural selection was hampered by his ignorance of the particulate nature of inheritance. I suggest, instead, that Darwin was handicapped by an inability to effectively engage in quantitative population thinking. I also question Godfrey-Smith’s understanding of the role that Malthusian struggle plays in linking natural selection to the origination of new adaptive traits, and I (...) raise problems for his defence of apparently unproblematic conceptions of human nature. Finally, I highlight the welcome conception of a ‘philosophy of nature’ developed by Godfrey-Smith. (shrink)

Here is one way that philosophers and biologists sometimes speak of Darwin’s explanatory innovation: ‘Eyes, organs of echolocation, camouflage and the like are all wonderful instances of contrivance, of complex adaptation, of good design. Paley and the other natural theologians sought to explain this good design by appeal to an intelligent designer. Darwin, on the other hand, offers us a superior explanation for the appearance of this same property: Darwin shows us that we can explain good design through the action (...) of selection. Indeed, selection is the only process that can explain good design in nature. And that is why evolutionary biologists can continue to use a version of the argument from design called the argument from biological design: when we see an instance of good design in nature, we should infer not the guiding hand of God, but the hand of selection at work.’ -/- . (shrink)

The Price Equation is a powerful, and unusual, tool within evolutionary theory. Because it is completely general in application, and also very nearly free of distorting idealisations, the Price Equation is widely regarded as having exceptional power for understanding evolutionary change. It is no surprise, then, that it has been applied to many different contexts outside of traditional ‘organic’ evolution, including the domain of cultural evolution. In this essay I argue for various ways in which the Price Equation can mislead (...) about cultural evolutionary theory. They all derive from difficulties that processes of cultural reproduction pose for attempts to distinguish ‘selection’ from ‘transmission’. This does not mean the cultural Price Equation is of no use: its value remains as an analytical tool in those circumstances where a distinction between selection and transmission can be drawn without too much distortion. (shrink)

We distinguish dynamical and statistical interpretations of evolutionary theory. We argue that only the statistical interpretation preserves the presumed relation between natural selection and drift. On these grounds we claim that the dynamical conception of evolutionary theory as a theory of forces is mistaken. Selection and drift are not forces. Nor do selection and drift explanations appeal to the (sub-population-level) causes of population level change. Instead they explain by appeal to the statistical structure of populations. We briefly discuss the implications (...) of the statistical interpretation of selection for various debates within the philosophy of biologythe `explananda of selection' debate and the `units of selection' debate. (shrink)