The development of action representation during adolescence was investigated using a visually guided pointing motor task to test motor imagery. Forty adolescents and 33 adults were instructed to both execute and imagine hand movements from a starting point to a target of varying size. Reaction time was measured for both Execution and Imagery conditions. There is typically a close association between time taken to execute and image actions in adults because action execution and action simulation rely on overlapping neural circuitry. (...) Further, representations of actions are governed by the same speed-accuracy trade-off as real actions, as expressed by Fitts’ Law. In the current study, performance on the VGPT in both adolescents and adults conformed to Fitts’ Law in E and I conditions. However, the strength of association between E and I significantly increased with age, reflecting a refinement in action representation between adolescence and adulthood. (shrink)

Adolescent brain development has become an important target for governments to act upon, in the name of healthy individuals and economic prosperity. In the Foresight Project on Mental Capital and Wellbeing , initiated by the Government Office for Science, adolescent behaviour was identified as one of the key challenges for UK policy. The report draws on 'state of the art′ evidence from scientific experts, to recommend ways in which to 'capitalize′ on mental faculties to improve, boost, and make maximum use (...) of the cognitive resources and mental health of individuals during the entire lifespan. Specifically, through a close analysis of the category of adolescence in cognitive neuroscience, we examine the perspective of personhood espoused by MCW. We show how the notion of 'plasticity′, which underpins the recommendations about how to “make the most” of adolescents′ developing brains and cognitive resources, creates vital linkages between neuroscience and neosocial policy. (shrink)

Malnutrition among children is prevalent in almost all the states in India. This study assesses the extent and causes of malnutrition in two eastern Indian states with similar climates, namely West Bengal and Assam, using data from the National Family Health Survey 1998s educational status, working status of the mother, mother’s age at delivery of the children, source of drinking water, toilet facilities and standard of living of the household. Logistic regression was carried out separately for each of the three (...) indices on the explanatory variables for both the states. It was found that not all variables are equally important in determining whether a baby is underweight, or suffering from acute or chronic malnutrition. Also, the importance of variables is not the same in the two states. It was observed that the coefficients associated with the variables in determining weight-for-height are not significant compared with those for weight-for-age and height-for-age. (shrink)

True Hinduism has a power and beauty that no one acquainted with it can regard with anything but the deepest respect. This book contains a range of scriptures, an array of ritualistic procedures and traditions of brahminical orthodoxy, varied interpretations coupled with multiple views. True Hinduism has a power and beauty that no one acquainted with it can regard with anything but the deepest respect. You have to approach it as you approach poetry, with a willing suspension of disbelief. Above (...) all the peripheral myths, customs, beliefs and rites, rises the great. (shrink)

The National Blood Policy in India relies heavily on voluntary blood donors, as they are usually assumed to be associated with low levels of transfusion-transmitted infections . In India, it is mandatory to test every unit of blood collected for hepatitis B, hepatitis C, HIV/AIDS, syphilis and malaria. Donors come to the blood bank with altruistic intentions. If donors test positive to any of the five infections, their blood is discarded. Although the blood policy advocates disclosure of TTI status, donors (...) are not, in practice, informed about their results. The onus is on the donor to contact the blood bank. Out of approximately 16 000 donations in the past 2 years, 438 tested positive for TTI, including 107 for HIV. Only 20% of the donors contacted the blood bank; none of them were HIV positive. Disclosure by blood banks of TTI status by telephone or mail has resulted in serious consequences for some donors. Health providers face an ethical dilemma, in the absence of proper mechanisms in place for disclosure of test results, regarding notification to donors who may test positive but remain ignorant of their TTI status. Given the high cost of neglecting to notify infected donors, the authors strongly recommend the use of rapid tests before collecting blood, instead of the current practice, which takes 3 h to obtain results, and disclosure of results directly to the donor by a counsellor, to avoid dropouts and to ensure confidentiality. (shrink)

This handbook provides a comprehensive overview of Islamic ethical issues within a wide spectrum of philosophy of science topics, examining the development of the model of moral inclusiveness in economics, science and society from ontological, epistemological and analytical perspectives. This paradigm takes the view that ethics is systemically endogenous, and can be studied by the most rigorous scientific analysis pertaining to diverse issues and problems of ethicality in socio-scientific inquiry. This handbook takes a sweeping transdisciplinary approach that is deeply phenomenological, (...) to the nature and logic of scientific inquiry of, and in, the Qur’an. Such an approach invokes the episteme of the unity of knowledge in the socio-scientific systemic sense. The volumes' respective sections focus on the nature, logic, and role that ethics plays in formulating new vistas of alternative epistemic futures in Islamic economics, finance, and the social sciences. The ideas presented are situated within the broader context of the post-modernist, post-pandemic, and the post-Covid-19 epoch, while being aimed at conceptualising a distinctive new outlook of transdisciplinary intellection in Islamic philosophy. The content is rigorously conceptual, qualitative, quantitative, and applied. Covering a diversity of subject areas from philosophy of science, to economics and in socio-scientific context within the realm of Islamic philosophy, this forms a key text for scholars in these respective arenas, led by pioneering scholarship in Islamic studies. (shrink)

This book investigates morality in a socio-scientific worldview, examining the epistemology of existence in conjunction with Islamic monotheistic law to generate a world-system that governs action and reaction in the context of a variety of cognitive and social environments.

Written in honor of Dale K. Van Kley, leading specialist on religion and politics in the Old Regime and the French Revolution, these essays examine how Jansenist belief shaped enlightenment ideas, cultural identities, social relations and politics in France throughout the long eighteenth century. Van Kley's work has invited scholars to think beyond the traditional parameters of the Enlightenment and to consider how religious faith functioned in the broader context of Old Regime, Revolutionary, and post-Revolutionary France. In different ways, each (...) essay challenges the idea of an inherent opposition between faith and Enlightenment, which likewise equates modernity with secularization. The authors within this volume address two main questions. Firstly, how did religious belief continue to shape identities and experiences in the long eighteenth century? Secondly, how does this narrative of enduring religious belief in eighteenth-century France help historians rethink the Enlightenment and the French Revolution? The various methodologies used by the contributors illustrate how belief, Enlightenment, and Revolution coexisted and indeed co-mingled in different contexts: politics and political culture, the social and cultural history of ideas, and the history of material culture. (shrink)

Maswood and Rajaram examine the transmission of false memories across small and larger networks. While the spread of false memories is not inherently beneficial, Maswood & Rajaram argued that a better understanding of the formation and propagation of false memories has practical and societal implications. For example, by better understanding how false memories transmit across groups, we might be better equipped to prevent detrimental behaviors that arise as a result of “fake news.”.

It is hypothesised that threatening stimuli are detected better due to their salience or physical properties. However, these stimuli are typically embedded in a rich context, motivating the question whether threat detection is facilitated via learning of contexts in which threat stimuli appear. To address this question, we presented threatening face targets in new or old spatial configurations consisting of schematic faces and found that detection of threatening targets was faster in old configurations. This indicates that individuals are able to (...) learn regularities within visual contexts and use this contextual information to guide detection of threatening targets. Next, we presented threatening and non-threatening face targets embedded in new or old spatial configurations. Detection of threatening targets was facilitated in old configurations, and this effect was reversed for non-threatening targets. Present findings show that detection of threatening targets is driven not only by stimulus properties as theorised traditionally but also by learning of contexts in which threatening stimuli appear. Further, results show that context learning for threatening targets obstructs context learning for non-threatening targets. Overall, in addition to typically emphasised bottom-up factors, our findings highlight the importance of top-down factors such as context and learning in detection of salient, threatening stimuli. (shrink)

Recent advances in genomic and imaging techniques have revealed the complex manner of organizing billions of base pairs of DNA necessary for maintaining their functionality and ensuring the proper expression of genetic information. The SMC proteins and cohesin complex primarily contribute to forming higher‐order chromatin structures, such as chromosomal territories, compartments, topologically associating domains (TADs) and chromatin loops anchored by CCCTC‐binding factor (CTCF) protein or other genome organizers. Cohesin plays a fundamental role in chromatin organization, gene expression and regulation. This (...) review aims to describe the current understanding of the dynamic nature of the cohesin‐DNA complex and its dependence on cohesin for genome maintenance. We discuss the current 3C technique and numerous bioinformatics pipelines used to comprehend structural genomics and epigenetics focusing on the analysis of Cohesin‐centred interactions. We also incorporate our present comprehension of Loop Extrusion (LE) and insights from stochastic modelling. (shrink)

This essay introduces the second installment of a symposium in Common Knowledge called “Apology for Quietism.” This introductory piece concerns the sociology of quietism and why, given the supposed quietude of quietists, there is such a thing at all. Dealing first with the “activist” Susan Sontag's attraction to the “quietist” Simone Weil, it then concentrates on the “activist” William Empson's attraction to the Buddha and to Buddhist quietism, with special reference to Empson's lost manuscript Asymmetry in Buddha Faces. The author, (...) who is also editor of the journal, argues against the effort of some contributors to substitute new terms for quietism and emphasizes instead what he calls “the need for repose.”. (shrink)

This essay introduces the second installment of a symposium in Common Knowledge called “Apology for Quietism.” This introductory piece concerns the sociology of quietism and why, given the supposed quietude of quietists, there is such a thing at all. Dealing first with the “activist” Susan Sontag's attraction to the “quietist” Simone Weil, it then concentrates on the “activist” William Empson's attraction to the Buddha and to Buddhist quietism, with special reference to Empson's lost manuscript Asymmetry in Buddha Faces (and to (...) Sharon Cameron's work on the topic in her book Impersonality). The author, who is also editor of the journal, argues against the effort of some contributors to substitute new terms for quietism and emphasizes instead what he calls (quoting Sontag) “the need for repose.”. (shrink)

ABSTRACTIn earlier work we showed that individuals learn the spatial regularities within contexts and use this knowledge to guide detection of threatening targets embedded in these contexts. While it is highly adaptive for humans to use contextual learning to detect threats, it is equally adaptive for individuals to flexibly readjust behaviour when contexts once associated with threatening stimuli begin to be associated with benign stimuli, and vice versa. Here, we presented face targets varying in salience in new or old spatial (...) configurations and changed the target salience halfway through the experiment to examine if contextual learning changes with the change in target salience. Detection of threatening targets was faster in old than new configurations and this learning persisted even after the target changed to non-threatening. However, the same pattern was not seen when the targets changed from non-threatening... (shrink)

This paper contains two traditions of diagrammatic studies namely one, the Euler–Venn–Peirce diagram and the other, following tradition of Aristotle, the square of oppositions. We put together both the traditions to study representations of singular propositions, their negations and the inter relationship between the two. Along with classical negation we have incorporated negation of another kind viz. absence. We have also considered the changes that take place in the context of open universe.

In developed economies, powerful legislative and regulatory frameworks, for people with disability over the last five decades, have provided major motivation for business compliance with disability in the workplaces. However, developing economy like India is marked by emergent disability legislation, weak institutional enforcement and an evolving disability rights movement. In the absence of strong institutional expectations, the private sector’s role in mainstreaming the disability agenda has been largely an act of voluntary participation. Drawing upon an in-depth, multilevel, cross-functional qualitative study (...) of four Indian information technology sector companies, this paper explores why these companies engage in pro-social corporate behaviour in favour of disability. The study locates itself in the context of conceptualization of PWD as employee stakeholders and the literature on strategic CSR. The findings reveal that strategic factors promote voluntary business engagement with disability at workplaces and contribute to understanding of workplace integration of minority employees. (shrink)

Choudhury, elected president of the General Assembly in 1986, reviews the changes within the UN and reasserts its enduring role as a global instrument of peace.

Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory approach that asked what future envisioned knowledge systems might need to look like and how we might get there. Findings suggest that envisioned future systems will need (...) to be much more collaborative, open, diverse, egalitarian, and able to work with values and systemic issues. They will also need to go beyond producing knowledge about our world to generating wisdom about how to act within it. To get to envisioned systems we will need to rapidly scale methodological innovations, connect innovators, and creatively accelerate learning about working with intractable challenges. We will also need to create new funding schemes, a global knowledge commons, and challenge deeply held assumptions. To genuinely be a creative force in supporting longevity of human and non-human life on our planet, the shift in knowledge systems will probably need to be at the scale of the enlightenment and speed of the scientific and technological revolution accompanying the second World War. This will require bold and strategic action from governments, scientists, civic society and sustained transformational intent. (shrink)

An examination of seventeenth- and eighteenth-century French history indicates that the relationship between the Jesuits and Quietism was shaped by politics as well as by concerns of theological orthodoxy. During the late 1690s, the Jesuits championed François Fénelon accused of Quietism at the same time as they spearheaded an attack against Quietism in Burgundy, emphasizing crimes of spiritual incest or the abuse of clerical authority. Such ambiguity indicates that the Jesuits were motivated by a desire to consolidate political power in (...) Louis XIV... trades court. However, the fusion of Quietist heresy, charges of spiritual incest, and political gamesmanship would ultimately make the Jesuits themselves vulnerable to claims of heresy and abuse when the Girard/Cadière affair became a national scandal in 1731. This essay argues that this disquiet over clerical behavior and power was articulated in a changing political culture between the late seventeenth century and the 1730s. Growing dissatisfaction against the crown established a new political consciousness, one that regarded the politics of secrecy as problematic if not outright illegitimate. The secrecy of the confession, the emphasis on interiority seemingly at the expense of morality, and the enigmatic language of mysticism, all associated with Quietism played into fears of clerical (or “Jesuit”) cabal and conspiracy. When Jesuit opponents linked the order to Quietism, they presented the Jesuits as threats to an emerging set of political values in which legitimate authority was transparent and open while illegitimate power operated in the shadows. (shrink)

The scientific methodology underlying model-building is critically investigated. The modeling views of Popper and Samuelson and their prototypes are critically examined in the light of the theme of the moral law of unity of knowledge and unity of the world-system configured by the meta-epistemology of organic unity of knowledge. Upon such critical examination of received methodology of model-building in economics, the extended perspective?namely of integrating the moral law derived from the divine roots as the meta-epistemology?is rigorously studied. The example of (...) the Islamic prerogative in interpreting the holistic world-system through model-building in economics is highlighted. A religio-philosophical approach is adopted to exemplify some approaches in Islamic model-building. An especial focus is placed here on grassroots types of financing and activities. The critique of these models within the existing Islamic scholarship is carried out. The result is new dimensions of macroeconomic analysis that emanate in a logical way from the meta-epistemological approach, and oppose the mainstream ideas, both in received and Islamic economic thinking as of now. (shrink)

The epistemological foundation of unity of knowledge is used to formulate a system-model of participatory socioeconomic development. The micro-properties of such a participatory development approach are deeply ethical in nature. In order to bring out the endogenous role of ethics derived from the moral law in reference to the epistemic foundation, and thereby explain their impact on the socioeconomic development experience, the methods of topological space and topological mappings are found to be appropriate for formalizing the complex nature of participatory (...) dynamics. They emerge in the midst of institutional and organic interaction, integration, and evolution. The application of topological methods to participatory socioeconomic development thus opens up a field that is rarely used by mathematical economists. In this sense this article is an original contribution to the area of ethical development theory and its topological explanation and application. (shrink)

We investigate the evolution of linear density contrasts obtained with respect to a homogeneous spatially flat Friedman-Lemaître–Robertson–Walker background by solving the density contrast equations governed by Newtonian and MONDian force laws using symmetry-based approach. We find eight-parameter Lie group symmetries for the linear order density perturbation equation for the Newtonian case whereas the density contrast equation follows only one parameter Lie group symmetry in MONDian case. We use Lie symmetries to find the group invariant solutions from invariant curve condition. The (...) physical features of the evolution for various mode of density contrast with respect to the global cosmic background density in homogeneous isotropic cosmological models have been investigated using analytical group invariant solutions along with their numerical solutions. An account for cosmological density contrast and mass fluctuation also have been provided. We also have shown that the MONDian force law generates higher amplitudes in the density fluctuation, results in a more rapid structure formation that cannot be possible under the Newtonian force law. (shrink)

This essay presents some preliminary thoughts about the linkages between current human rights universalism and the practice of violence in the form of wars and interventions. I draw three parallels that may help us think about the current wars on terror and in Iraq. The first parallel concerns the progress of liberal universalist thought from the Enlightenment period in which a concern for rights coexisted with the justifications for imperialism. In the current era the succeeding line of universalist thought is (...) that of human rights which similarly coexists with the overt and tacit support for violence that deprives some humans of their lives.The second parallel concerns the use of national identity. In the imperial era, the justification for rights either given or withheld was closely linked to constructions of national identity. Similarly, today there is a resurgence of nationalist discourse in which the construction of U.S. national identity is used to justify the violence that is done against Iraqi citizens. This discourse which constructs the U.S. as ontologically civilized and the Iraqis as barbarians is used to justify the violence that is done to them.Finally, the last parallel concerns violence in general. During imperialism, the scrutiny for acts of violence was borne largely by the native. Because he was constructed as a barbarian, his violence was made far more obvious as further evidence of his lesser development. In the present circumstances, a similar scrutiny is borne by the Iraqi insurgent while the violence of the coalition forces remains veiled beneath euphemisms like collateral damage. The torture scandal at Abu-Ghraib presented an opportunity to reverse the gaze but because of its interpretation as an aberration that falls squarely outside the ``normal" and the failure to widen the debate to other violence, this opportunity was largely lost.These three parallels taken together suggest that the old liberal hegemonic order of imperialism with its conflicting narratives of rights and oppression has been carried forward and sublimated into a human rights regime. And human rights is now deployed to justify violence against ``human rights abusers." Because of this continuity, there is a need to create a new universalism born organically from the struggles of subordinated peoples that eliminates old-order imperialist justifications for the oppression of Others while claiming to support human rights. (shrink)

BackgroundAdverse Childhood Experiences have been associated with long-term physical and mental health conditions, toxic stress levels, developing unstable interpersonal relationships, and substance use disorders due to unresolved childhood adversities.AimsThis study assessed the perspectives of mental health providers regarding their adult patients’ coping with ACEs during COVID-19 in Houston, Texas. Specifically, we explored how individuals with ACEs are coping with the increased stresses of the pandemic, how MHPs may provide therapeutic support for individuals with ACEs during this pandemic, pandemic-related challenges of (...) accessing and utilizing mental health services for individuals with ACEs, and the awareness and treatment of ACEs among MHPs.MethodsTen in-depth semi-structured virtual interviews were conducted with licensed MHPs from November 2021 to April 2022 in Houston, Texas. Interviews were coded and analyzed for emerging themes through an inductive open coding approach to discover insights regarding coping with ACEs during COVID-19.ResultsFour key themes experienced by individuals with ACEs emerged from the MHP interviews: Maladaptive emotional dissonance and coping outlets during the pandemic, Difficulties with social connectedness and significance of social support, Heightened daily life stressors and coping with the ongoing disruption of the pandemic, and Changing interactions with the mental health system. Themes from this study highlighted that resilience, seeking treatment, and strong social support can help develop healthy coping strategies among individuals with ACEs.ConclusionThis study may help inform best clinical practices to develop interventions and policies regarding ACEs such as a resilience-promotion approach that targets all the socio-ecological levels. In addition, findings highlight the synergy of psychotherapeutic and pharmacological management via tele-health modalities, in helping individuals with ACEs continue receiving the care they deserve and need during a persistent pandemic and an uncertain future. (shrink)

Australia and India have had few reasons in the past to develop systematic and significant levels of economic engagement. This was due to very different positions they have held in the world-system since the Second World War. De-colonization, the fall of the British Empire, the weak status of the British Commonwealth, and the realpolitik of the Cold War saw India and Australia located on different parts of the geo-political and economic world map with small demographic and cultural flows, and insignificant (...) economic trade. Both countries developed similar economic policy regimes that were essentially state-led nationalist projects of economic development with concomitant policies of import-substitution, local industry-subsidization, highly-regulated financial systems, and high tariffs. The last quarter of the 20th century saw a radical revision of both nations’ economic strategies, with Australia moving first to drop many of its trade barriers in the 1970s and ’80s. It is now one of the most open economies in the world. India’s liberalization programme commenced much later in 1991 but nonetheless has had a dramatic impact on its economic fortunes and growing status in the world economy. With these changes there are increasing opportunities for bilateral trade and a greater economic enmeshment in regional engagements and alignments in the Indian Ocean and in wider Asian fora. One significant indicator of change in growing Australia-India economic engagement is to look at Foreign Direct Investment (hereafter FDI). Currently, the movement of FDI between these two countries is still not very large but has a strong potential to grow over the short to medium term. This paper looks at the future prospect of this growth and asserts that, by engaging in areas of comparative advantage, it will benefit both national economies. Moreover, economic flows are also indicators of great social and cultural traffic. The movement of FDI between the two countries will not only encourage greater flow of peoples, especially outward migration from India to Australia, but also trigger more Australian expatriates living in India (from a very low base). Greater economic trade promises more cultural exchange. (shrink)