The paper studies various functions of Berzelian formulas in European organic chemistry prior to the mid-nineteenth century from a semiotic, historical and epistemological perspective. I argue that chemists applied Berzelian formulas as productive ‘paper tools’ for creating a chemical order in the ‘jungle’ of organic chemistry. Beginning in the late 1820s, chemists applied chemical formulas to build models of the binary constitution of organic compounds in analogy to inorganic compounds. Based on these formula models, they constructed new classifications of organic (...) substances. They further applied Berzelian formulas in a twofold way to experimentally investigate organic chemical reactions: as tools which supplemented laboratory tools and as tools for constructing interpretive models of organic reactions. The scrutiny of chemists' performances with chemical formulas on paper also reveals a dialectic which contributed considerably to the formation of the new experimental culture of synthetic carbon chemistry that emerged between the late 1820s and the early 1840s. In an unintended and unforeseen way, the tools reacted back on the goals of their users and contributed to conceptual development and a shift of scientific objects and practices which transcended the originally intended chemical order. (shrink)

This paper studies European chemists’ shifting ontologies of materials by comparing the ways in which they classified materials. The focus is on plant materials, their different identities, and the changing ways chemists sorted out and ordered plant materials in the eighteenth and early nineteenth centuries. The main goals of the paper are to follow the development of plant materials from ordinary, everyday materials and commodities in the early eighteenth century to purified carbon compounds and organic substances familiar only to experts (...) in the 1830s, and to reconstruct chemists’ ways of classifying these objects in different practical and intellectual contexts.The study of changes in European chemists’ ways of classifying plant materials over more than a century brings to the foreground a trajectory of ontological shifts that is ‘punctuated’ in the 1750s, the 1790s, and the 1830s. Early eighteenth-century plant materials, which were commodities of the apothecary trade and other arts and crafts, were elevated epistemically as compound components or ‘proximate principles’ of plants in the 1750s, reduced to organic compounds in the 1790s, and replaced by carbon compounds in the 1830s. The last, third transformation of the epistemic constitution of materials and the mode of their classification was accompanied by a deep transformation of the material culture of plant chemistry. After the late 1830s, many of the eighteenth-century vegetable commodities disappeared from chemists’ agenda or were split into different substances individuated and identified in new ways. Coal tar products, and new organic artefacts containing chlorine or bromine, entered the chemical laboratory in the 1820s and became fused with the purified rest of the previous plant and animal substances. The material objects of the new culture of organic chemistry became detached from the materials applied in the extant arts and crafts. It was only in the late 1850s, with the rise of the synthetic dye industry, that a great number of these laboratory substances became involved in industrial production.Keywords: Commodities and scientific objects; Historical ontology; Classification; Plant chemistry; Organic chemistry. (shrink)

The ArgumentMost historians of science share the conviction that the incorporation of the corpuscular theory into seventeenth-century chemistry was the beginning of modern chemistry. My thesis in this paper is that modern chemisty started with the concept of the chemicl compound, which emerged at the end of the seventeenth and the beginning of the eighteenth century, without any signifivant influence of the corpuscular theory. Rather the historical reconstruction of the emergence of this concept shows that it resulted from the reflection (...) on the chemical operations in the sixteenth-century metallurgy and seventeenth-century pharmacy. I argue that the reversibility of these operations and their understanding as crafts (metallurgy) or chemical arts (pharmacy) were decisive factors for the emergence of the first ideas about chemical compounds in the seventeenth-century pharmaceutical works written by pharmaceutically trained authors, influenced by the Paracelsian image of nature. There is a direct line of descent from these authors to E.F.Geoffroy (1675–1742), who integrated the first scattered ideas of chemical compound into a general concept comprising chemical artefacts as well as natural bodies. (shrink)

I argue and demonstrate in this essay that interconnected systems of science and technology, or technoscience, existed long before the late nineteenth century, and that eighteenth-century chemistry was such an early form of technoscience. Based on recent historical research on the early development of carbon chemistry from the late 1820s until the 1840s—which revealed that early carbon chemistry was an experimental expert culture that was largely detached from the mundane industrial world—I further examine the question of the internal preconditions within (...) the expert culture of carbon chemistry that contributed to its convergence with the synthetic-dye industry in the late 1850s. I argue that the introduction of new types and techniques of organic-chemical reactions and organic substances in this experimental expert culture, along with the application of chemical formulae as paper tools for modeling reactions as well as the chemical constitution and structure of substances, enabled academic chemists to make specific, novel contributions to chemical technology and industry in the second half of the nineteenth century. (shrink)

The ArgumentThe overall portrayal of early modern experimentation as a new method of securing assent within a philosophical discourse sketched in many of the recent studies on the historical origin of experimentation is questioned by the analysis of the experimental practice of chemistry at the Paris Academy. Chemical experimentation at the Paris Academy in the late seventeenth and early eighteenth century originated in a different tradition than the philosophical. It continued and developed the material culture of the chemical work shops (...) of the sixteenth and seventeenth centuries, and explored epistemic objects which had rather loose connections to philosophy. On the other hand, I argue against the classical dichotomy between the work of the mind that of the hand, and for an epistemology of experimentation that acknowledges that experimental manipulation goes hand in hand with reflexion. In particuler, I argue against the view that chemists at the Paris Academy were “pragmatists” who merely gathered experimental facts and classified substances and operations without perplexing themselves over general conceptions. I claim that the chemists at the Paris Academy constructed a general conception framework which shaped the significance of their experiments. This conception that I call conception of the chemical combination, compound and reaction was rather quickly reified into an experimental fact. Despite its generality it was a genuine chemical conception rather independent of philosophy. (shrink)

Summary From summer 1792 until spring 1797, Alexander von Humboldt was a mining official in the Franconian parts of Prussia. He visited mines, inspected smelting works, calculated budgets, wrote official reports, founded a mining school, performed technological experiments, and invented a miners’ lamp and respirator. At the same time he also participated in the Republic of Letters, corresponded with savants in all Europe, and was a member of the Leopoldine Carolinian Academy and the Berlin Gesellschaft Naturforschender Freunde. He collected minerals, (...) made geognostic observations, performed chemical and physiological experiments, read the newest scientific journals, and prepared and published texts on mineralogy, geognosy, chemistry, botany and physiology. Humboldt did his scientific investigations alongside his administrative and technical work. This raises the question of whether there were fruitful interactions between Humboldt's technical-administrative work and (parts of) his natural inquiry. I argue that the mining official Humboldt was a late eighteenth-century figure of hybrid savant-technician. Mines and smelting works provided numerous opportunities for studies of nature. Humboldt systematically used inspection tours for mineralogical and geognostic observations. He transformed mines into chemical laboratories, and he transferred knowledge and material items from his natural inquiries in mines to academic institutions. The main objective of this paper is to illuminate the persona of savant-technician (or scientific-technological expert) along with Humboldt's mixed technological and scientific work during his term as mining official. (shrink)

ABSTRACT An examination of the use of the word “laboratory” before the nineteenth century yields two striking results. First, “laboratory” referred almost exclusively to a room or house where chemical operations such as distillation, combustion, and dissolution were performed. Second, a “laboratory” was not exclusively a scientific institution but also an artisanal workplace. Drawing on the historical actors' use of “laboratory,” the essay first presents (some necessarily scattered) evidence for the actual correspondence between artisanal and scientific laboratories in the eighteenth (...) century. A particularly instructive case is the way the equipment of the laboratory of the Prussian Academy of Sciences was acquired. There was, in this case, a direct transfer of instruments, vessels, and materials from a pharmaceutical to an academic laboratory. The essay then argues that we ought to distinguish between two different experimental traditions in the early modern period: experimental philosophy and the laboratory tradition that meshed studies of nature with technological innovation. (shrink)

In the early eighteenth century, chemistry became the main academic locus where, in Francis Bacon's words, Experimenta lucifera were performed alongside Experimenta fructifera and where natural philosophy was coupled with natural history and 'experimental history' in the Baconian and Boyleian sense of an inventory and exploration of the extant operations of the arts and crafts. The Dutch social and political system and the institutional setting of the university of Leiden endorsed this empiricist, utilitarian orientation toward the sciences, which was forcefully (...) propagated by one of the university's most famous representatives in the first half of the eighteenth century, the professor of medicine, botany and chemistry Herman Boerhaave. Recent historical investigations on Boerhaave's chemistry have provided important insights into Boerhaave's religious background, his theoretical and philosophical goals, and his pedagogical agenda. But comparatively little attention has been paid to the chemical experiments presented in Boerhaave's famous chemical textbook, the Elementa chemiae, and to the question of how these experiments relate not only to experimental philosophy but also to experimental history and natural history, and to contemporary utilitarianism. I argue in this essay that Boerhaave shared a strong commitment to Baconian utilitarianism and empiricism with many other European chemists around the middle of the eighteenth century, in particular to what Bacon designated 'experimental history' and I will provide evidence for this claim through a careful analysis of Boerhaave's plant-chemical experiments presented in the Elementa chemiae. (shrink)

This paper studies the semiotic,epistemological and historical aspects of Berzelianformulas in early nineteenth-century organicchemistry. I argue that Berzelian formulas wereenormously productive `paper tools' for representingchemical reactions of organic substances, and forcreating different pathways of reactions. Moreover, myanalysis of Jean Dumas's application of Berzelianformulas to model the creation of chloral from alcoholand chlorine exemplifies the role played by chemicalformulas in conceptual development (the concept ofsubstitution). Studying the dialectic of chemists'collectively shared goals and tools, I argue thatpaper tools, like laboratory instruments, areresources (...) whose possibilities are not exhausted byscientists' attempts to achieve existing goals, butrather whose applications generate new goals. The term`paper tools' is introduced to emphasize that thepragmatic and syntactic aspects of symbol systems arefully comparable to physical laboratory tools. (shrink)

The paper examines differences of styles of experimentation in the history of science. It presents arguments for a historization of our historial and philosophical notion of "experimentation," which question the common view that "experimental philosophy" was the only style of experimentation in the eighteenth and early nineteenth centuries. It argues, in particular, that "experimental history" and technological inquiry were accepted styles of academic experimentation at the time. These arguments are corroborated by a careful analysis of a case study, which is (...) embedded in a comparative historical overview. (shrink)

After the Seven Years War, the Prussian administration launched a campaign for useful knowledge and scientific education of state officials. This essay scrutinizes efforts undertaken around 1770 by the Central Prussian Administration for Mining and Smelting Works to establish the “mining sciences” and a mining school in the city of Berlin. As a result, from October 1770 on this Administration supported the public teaching in Berlin of mathematics, mechanics, mineralogy, metallurgy, chemistry and other areas of knowledge that constituted the “mining (...) sciences.” In so doing, it promoted the interconnection of scientific and technological knowledge. Contrary to common belief, however, a mining school or academy was not established in eighteenth-century Berlin. (shrink)

: I argue and demonstrate in this essay that interconnected systems of science and technology, or technoscience, existed long before the late nineteenth century, and that eighteenth-century chemistry was such an early form of technoscience. Based on recent historical research on the early development of carbon chemistry from the late 1820s until the 1840s—which revealed that early carbon chemistry was an experimental expert culture that was largely detached from the mundane industrial world—I further examine the question of the internal preconditions (...) within the expert culture of carbon chemistry that contributed to its convergence with the synthetic-dye industry in the late 1850s. I argue that the introduction of new types and techniques of organic-chemical reactions and organic substances in this experimental expert culture, along with the application of chemical formulae as paper tools for modeling reactions as well as the chemical constitution and structure of substances, enabled academic chemists to make specific, novel contributions to chemical technology and industry in the second half of the nineteenth century. (shrink)

Summary In the second half of the eighteenth century, the Prussian State supported savants who combined learned inquiry into nature with technical work. Members of the physical and mathematical classes of the Royal Prussian Academy of Sciences were involved in State projects such as surveying for the construction of canals, chemical analysis of Silesian iron, production of porcelain and of beet sugar. Some of these men were truly ‘hybrid’ experts living both in the worlds of State-directed manufacture and academic natural (...) inquiry. Among these savant experts there was a particular sub-group that is at the centre of this paper: mining officials who were also recognized as mineralogists, geologists and chemists. The paper describes and analyses the training and the varied technical and scientific activities of these ‘savant officials’. At the centre of attention are the travels of inspection of the mineralogist and mining official Carl Abraham Gerhard (1738–1821) in the late 1760s. I argue that Gerhard's travels of inspection were at the same time geological travels and that savant officials like Gerhard made a significant contribution to the fledgling science of geology. (shrink)

I argue in the paper that classical chemistry is a science predominantly concerned with material substances, both useful materials and pure chemical substances restricted to scientific laboratory studies. The central epistemological and methodological status of material substances corresponds with the material productivity of classical chemistry and its way of producing experimental traces. I further argue that chemist’s ‘pure substances’ have a history, conceptually and materially, and I follow their conceptual history from the Paracelsian concept of purity to the modern concept (...) of pure stoichiometric compounds. The history of the concept of ‘pure substances’ shows that modern chemists’ concept of purity abstracted from usefulness rather than being opposed to it. Thus modern chemists’ interest in pure chemical substances does not presuppose a concept of pure science. (shrink)

E.F. Geoffroy's table of different relations ( rapports ) between different chemical substances is mainly based on empirical knowledge accumulated in 16th and 17th century metallurgy and pharmacy. The substances listed in the left half of the table were basic for the formation of salts which were produced for medical ends in the chemical-pharmaceutical practice of the 17th century. The right half of the table refers to substances and operations of metallurgy which had already been described in the metallurgical writings (...) of the 16th century. Even Geoffroy's ordering of the substances within the columns of his table has its origin in metallurgical and pharmaceutical practice. The key concept of the conceptual framework underlying the table and its commentary is the concept of chemical compound which emerged at the end of the 17th century. Geoffroy extends the range of application of this concept, which was first limited to chemical artefacts, to include natural bodies. Eliminating the peripatetical distinction between natural bodies and chemical artefacts he formulates a new research program, consisting in the determination of the laws of the relations ( rapports ) between different chemical substances. (shrink)

Ursula Klein and E. C. Spary : Materials and expertise in early modern Europe: Between market and laboratory. Chicago: University of Chicago Press, 2010, 408pp, $50 HB Content Type Journal Article DOI 10.1007/s11016-010-9462-8 Authors Jonathan Simon, LEPS-LIRDHIST, Université Lyon 1, Université de Lyon, 69622 Villeurbanne cedex, France Journal Metascience Online ISSN 1467-9981 Print ISSN 0815-0796.