This article provides practical guidance for researchers who wish to enroll and collect data from pediatric research participants through online and mobile platforms, with a focus on the involvement of both children and their parents in the decision to participate.

There is a growing consensus that results generated through multiplex genetic tests, even those produced as a part of research, should be reported to providers and patients when they are considered “actionable,” that is, when they could be used to inform some potentially beneficial clinical action. However, there remains controversy over the precise criterion that should be used in identifying when a result meets this standard. In this paper, we seek to refine the concept of “actionability” by exploring one proposed (...) use for genetic test results. We argue that genetic test results indicating that a patient is at risk for developing a chronic health condition should not be considered actionable if the only potential value of that result is to motivate patients to make changes in their health behaviors. Since the empirical research currently available on this question is equivocal, we explore relevant psychological theories of human motivation to demonstrate that current theory does not support the assumption that information about genetic risk will be motivating to most patients in their attempts to make changes in health behaviors. (shrink)

The COVID-19 pandemic has resulted in widespread disruption of the typical way of doing things. In nearly every industry, responses to the pandemic have brought about departures from standard opera...

As genomic science has evolved, so have policy and practice debates about how to describe and evaluate the ways in which genomic information is treated for individuals, institutions, and society. The term genetic exceptionalism, describing the concept that genetic information is special or unique, and specifically different from other kinds of medical information, has been utilized widely, but often counterproductively in these debates. We offer genomic contextualism as a new term to frame the characteristics of genomic science in the debates. (...) Using stasis theory to draw out the important connection between definitional issues and resulting policies, we argue that the framework of genomic contextualism is better suited to evaluating genomics and its policy-relevant features to arrive at more productive discussion and resolve policy debates. (shrink)

Mobile devices with health apps, direct-to-consumer genetic testing, crowd-sourced information, and other data sources have enabled research by new classes of researchers. Independent researchers, citizen scientists, patient-directed researchers, self-experimenters, and others are not covered by federal research regulations because they are not recipients of federal financial assistance or conducting research in anticipation of a submission to the FDA for approval of a new drug or medical device. This article addresses the difficult policy challenge of promoting the welfare and interests of (...) research participants, as well as the public, in the absence of regulatory requirements and without discouraging independent, innovative scientific inquiry. The article recommends a series of measures, including education, consultation, transparency, self-governance, and regulation to strike the appropriate balance. (shrink)

Beginning in the 20th century, scientific research came to be dominated by a growing class of credentialed, professional scientists who overwhelmingly displaced the learned amateurs of an earlier time. By the end of the century, however, the exclusive realm of professional scientists conducting research was joined, to a degree, by “citizen scientists.” The term originally encompassed non-professionals assisting professional scientists by contributing observations and measurements to ongoing research enterprises. These collaborations were especially common in the environmental sciences, where citizen scientists (...) participated in counting wildlife and measuring environmental conditions. Later, patient groups began to play a more active role in supporting clinical trials and collecting health records from affected individuals. (shrink)

Der Aufsatz analysiert den Konnex zwischen Individualisierter Medizin und der Forderung nach mehr gesundheitlicher Eigenverantwortung, der oft als plausibel angenommen wird, wenn der Individualisierten Medizin das Potential zugesprochen wird, das solidarisch finanzierte Gesundheitssystem in Deutschland zu transformieren. Ausgehend von einer logischen Rekonstruktion des Verantwortungsbegriffs, die dessen Operationalisierbarkeit unter anderem an Sanktionsvollmachten der jeweiligen Verantwortungsinstanz bindet, und basierend auf einem terminologisch präzisierten Verständnis von Individualisierter Medizin wird folgende These entwickelt: Die Annahme, im Rahmen Individualisierter Medizin sei eine verlässliche Prädiktion anlagebedingter und (...) zugleich lebensstilabhängiger Erkrankungsrisiken möglich, verpflichtet logisch nicht zur Übernahme der Forderung, Lebensstile mit negativem Einfluss auf persönliche Erkrankungsrisiken seien zu sanktionieren. Weil die Forderung nach mehr gesundheitlicher Eigenverantwortung aus dem Programm der Individualisierten Medizin logisch nicht ohne Hinzunahme normativer Prinzipien abzuleiten ist, kann man dieses Programm selbst gut heißen, ohne sich die politische Forderung nach einem Umbau des solidarisch finanzierten Gesundheitssystems unter dem Vorzeichen gesundheitlicher Eigenverantwortung zu eigen machen zu müssen. (shrink)

ZusammenfassungDer Aufsatz analysiert den Konnex zwischen Individualisierter Medizin und der Forderung nach mehr gesundheitlicher Eigenverantwortung, der oft als plausibel angenommen wird, wenn der Individualisierten Medizin das Potential zugesprochen wird, das solidarisch finanzierte Gesundheitssystem in Deutschland zu transformieren. Ausgehend von einer logischen Rekonstruktion des Verantwortungsbegriffs, die dessen Operationalisierbarkeit unter anderem an Sanktionsvollmachten der jeweiligen Verantwortungsinstanz bindet, und basierend auf einem terminologisch präzisierten Verständnis von Individualisierter Medizin wird folgende These entwickelt: Die Annahme, im Rahmen Individualisierter Medizin sei eine verlässliche Prädiktion anlagebedingter und (...) zugleich lebensstilabhängiger Erkrankungsrisiken möglich, verpflichtet logisch nicht zur Übernahme der Forderung, Lebensstile mit negativem Einfluss auf persönliche Erkrankungsrisiken seien zu sanktionieren. Weil die Forderung nach mehr gesundheitlicher Eigenverantwortung aus dem Programm der Individualisierten Medizin logisch nicht ohne Hinzunahme normativer Prinzipien abzuleiten ist, kann man dieses Programm selbst gut heißen, ohne sich die politische Forderung nach einem Umbau des solidarisch finanzierten Gesundheitssystems unter dem Vorzeichen gesundheitlicher Eigenverantwortung zu eigen machen zu müssen. (shrink)

ZusammenfassungDer Aufsatz analysiert den Konnex zwischen Individualisierter Medizin und der Forderung nach mehr gesundheitlicher Eigenverantwortung, der oft als plausibel angenommen wird, wenn der Individualisierten Medizin das Potential zugesprochen wird, das solidarisch finanzierte Gesundheitssystem in Deutschland zu transformieren. Ausgehend von einer logischen Rekonstruktion des Verantwortungsbegriffs, die dessen Operationalisierbarkeit unter anderem an Sanktionsvollmachten der jeweiligen Verantwortungsinstanz bindet, und basierend auf einem terminologisch präzisierten Verständnis von Individualisierter Medizin wird folgende These entwickelt: Die Annahme, im Rahmen Individualisierter Medizin sei eine verlässliche Prädiktion anlagebedingter und (...) zugleich lebensstilabhängiger Erkrankungsrisiken möglich, verpflichtet logisch nicht zur Übernahme der Forderung, Lebensstile mit negativem Einfluss auf persönliche Erkrankungsrisiken seien zu sanktionieren. Weil die Forderung nach mehr gesundheitlicher Eigenverantwortung aus dem Programm der Individualisierten Medizin logisch nicht ohne Hinzunahme normativer Prinzipien abzuleiten ist, kann man dieses Programm selbst gut heißen, ohne sich die politische Forderung nach einem Umbau des solidarisch finanzierten Gesundheitssystems unter dem Vorzeichen gesundheitlicher Eigenverantwortung zu eigen machen zu müssen. (shrink)

¡Presente! develops a lived theology of nonviolence through an extended case study of the movement to close the School of the Americas (also known as the SOA or WHINSEC). Specifically,it analyzes how the presence of the dead—a presence proclaimed at the annual vigil of the School of the Americas Watch—shapes a distinctive, transnational, nonviolent movement. Kyle B.T. Lambelet argues that such a messianic affirmation need not devolve into violence or sectarianism and, in fact, generates practical reasoning. By developing a (...) messianic political theology in dialogue with the SOA Watch movement, Lambelet's work contributes to Christian ethics as he explores the political implications of the resurrection of the dead. This book contributes to studies of strategic nonviolence and civil resistance by demonstrating how religious and moral dynamics remain an essential part of such struggles. (shrink)

In this paper I take up the ambivalence we rightly feel toward leaders by examining the relationship between charismatic authority and moral exemplarity. Drawing on the social theory of Max Weber, and in dialogue with a case study of an anti-militarism movement called the SOA (School of Americas) Watch, I demonstrate that through a “politics of sacrifice” leaders synchronize their own stories with those of communally recognized exemplars and act in ways that evidence a solidarity in the suffering of those (...) exemplars thereby generating their charismatic authority. While performing crucial strategic, motivational, and pedagogical roles, this charisma also introduces problematic temptations to authoritarianism that short-circuit the practical reasoning that exemplars supposedly help to form. In the end this leaves our sense of ambivalence intact. What is needed, I argue, are practices of critique that reopen the distance between leader and follower and thus allow the possibility of practical reason. (shrink)

What should we make of the apocalyptic tone taken up by politicians, journalists, scientists, and activists? Some environmental thinkers such as Michael Shellenberger contend that alarming rhetoric distracts us from the technological and governance challenges presented by climate change. In the article, it is argued that retrieving a practical apocalyptic political theology from the Christian tradition can both clarify conceptual contradictions within this discourse as well as offer a practical orientation toward living within ecological endings. Amid the cascade of environmental (...) crises we are living through, apocalyptic practices of renunciation of the world offer a guide and discipline for living in the end. (shrink)

We look to mitonuclear ecology and the phenomenon of Mother’s Curse to argue that the sex of parents and offspring among populations of eukaryotic organisms, as well as the mitochondrial genome, ought to be taken into account in the conceptualization of evolutionary fitness. Subsequently, we show how characterizations of fitness considered by philosophers that do not take sex and the mitochondrial genome into account may suffer. Last, we reflect on the debate regarding the fundamentality of trait versus organism fitness and (...) gesture at the idea that the former lies at the conceptual basis of evolutionary theory. (shrink)

The psychedelic psilocybin has shown promise both as treatment for psychiatric conditions and as a means of improving well-being in healthy individuals. In some jurisdictions (e.g., Oregon, USA), psilocybin use for both purposes is or will soon be allowed and yet, public attitudes toward this shift are understudied. We asked a nationally representative sample of 795 US Americans to evaluate the moral status of psilocybin use in an appropriately licensed setting for either treatment of a psychiatric condition or well-being enhancement. (...) Showing strong bipartisan support, participants rated the individual’s decision as morally positive in both contexts. These results can inform effective policy-making decisions around supervised psilocybin use, given robust public attitudes as elicited in the context of an innovative regulatory model. We did not explore attitudes to psilocybin use in unsupervised or non-licensed community or social settings. (shrink)

In this issue of the American Journal of Bioethics, Kraft and colleagues (2018) provide important insights into the role trust plays in donor's decisions to contribute data and samples to local bio...

This paper examines the historical rise of both cardiopulmonary resuscitation and the do-not-resuscitate order and the wisdom of their continuing status in U.S. hospital practice and policy. The practice of universal presumed consent to CPR and the resulting DNR policy are the products of a particular time and were responses to particular problems. In order to keep the excesses of technology in check, the DNR policies emerged as a response to the in-hospital universal presumed consent to CPR. We live with (...) this historical concretion, which seems to perpetuate a false culture that the patient's wishes must be followed. The authors are critical of the current U.S. climate, where CPR and DNR are viewed as two among a panoply of patient choices, and point to UK practice as an alternative. They conclude that physicians in the United States should radically rethink approaches to CPR and DNR. (shrink)

Ideas for How to Take Wicked Problems Seriously Content Type Journal Article Pages 1-5 DOI 10.1007/s10806-011-9348-9 Authors Kyle Powys Whyte, Department of Philosophy, Michigan State University, 503 S. Kedzie Hall, East Lansing, MI 48824, USA Paul B. Thompson, Department of Philosophy, Michigan State University, 503 S. Kedzie Hall, East Lansing, MI 48824, USA Journal Journal of Agricultural and Environmental Ethics Online ISSN 1573-322X Print ISSN 1187-7863.

Pietraszewski asserts that social psychological research on groups is too vague, tautological, and dependent on intuitions to be theoretically useful. We disagree. Pietraszewski's contribution is thought-provoking but also incomplete and guilty of many of the faults he attributes to others. Instead of rototilling the existing knowledge landscape, we urge for more integration of new and old ideas.

Proponents of the problem of animal suffering state that the great amount of animal death and suffering found in Earth’s natural history provides evidence against the truth of theism. In particular, philosophers such as Paul Draper have argued that regardless of the antecedent probability of theism and naturalism, animal suffering provides positive evidence for the truth of naturalism over theism. While theists have attempted to provide answers to the problem of animal suffering, almost none have argued that animal suffering and (...) death can be seen as positive evidence for theism. This essay will discuss several arguments from the writings of Thomas Aquinas that can be used to show that animal suffering and death are to be expected in theistic universes. In the first section, I discuss evidential arguments for naturalism from animal suffering. Next, I provide an overview of Aquinas’ arguments, particularly in Book II of the Summa Contra Gentiles. After this, I discuss the implications these arguments have for theistic universes. Finally, I conclude that these arguments refute evidential arguments for naturalism from animal suffering and also provide evidence that favors theism. (shrink)

Stephen Law’s evil-god challenge is the argument that since an evil god is just as likely as the God of theism, there is no reason to believe that theism is true over believing there is a god who is omnipotent, omniscient, and omnimalevolent. There have been several attempts to answer the challenge, but recently John Collins has defended the evil-god challenge and also extended the argument past Law’s original formulation. In this article, I defend the classical theism of Thomas Aquinas (...) against the evil-god challenge. In particular, I explain how Aquinas’s theodicy involving God’s goodness and Aquinas’s privation view of evil avoid the challenge. (shrink)

This paper examines the historical rise of both cardiopulmonary resuscitation and the do-not-resuscitate order and the wisdom of their continuing status in U.S. hospital practice and policy. The practice of universal presumed consent to CPR and the resulting DNR policy are the products of a particular time and were responses to particular problems. In order to keep the excesses of technology in check, the DNR policies emerged as a response to the in-hospital universal presumed consent to CPR. We live with (...) this historical concretion, which seems to perpetuate a false culture that the patient's wishes must be followed. The authors are critical of the current U.S. climate, where CPR and DNR are viewed as two among a panoply of patient choices, and point to UK practice as an alternative. They conclude that physicians in the United States should radically rethink approaches to CPR and DNR. (shrink)

Provider claims to conscientious objection have generated a great deal of heated debate in recent years. However, the conflicts that arise when providers make claims to the "conscience" are only a subset of the more fundamental challenges that arise in health care practice when patients and providers come into conflict. In this piece, the author provides an account of patient-provider conflict from within the moral tradition of St. Thomas Aquinas. He argues that the practice of health care providers should be (...) understood as a form of practical reasoning and that this practical reasoning must necessarily incorporate both "moral" and "professional" commitments. In order to understand how the practical reasoning of provider should account for the needs and commitments of the patient and vice versa, he explores the account of dependence provided by Alasdair MacIntyre in his book Dependent Rational Animals. MacIntyre argues that St. Thomas’ account of practical reasoning should be extended and adapted to account for the embodied vulnerability of all humans. In light of this insight, providers must view patients not only as the subjects of their moral reflection but also as fellow humans upon whom the provider depends for feedback on the effectiveness and relevance of her practical reasoning. The author argues that this account precludes responsive providers from adopting either moral or professional conclusions on the appropriateness of interventions outside the individual circumstances that arise in particular situations. The adoption of this orientation toward patients will neither eradicate provider-patient conflict nor compel providers to perform interventions to which they object. But this account does require that providers attend meaningfully to the suffering of patients and seek feedback on whether their intervention has effectively addressed that suffering. (shrink)

Psychedelics such as psilocybin reliably produce significantly altered states of consciousness with a variety of subjectively experienced effects. These include certain changes to perception, cognition, and affect,1 which we refer to here as the acute subjective effects of psychedelics. In recent years, psychedelics such as psilocybin have also shown considerable promise as therapeutic agents when combined with talk therapy, for example, in the treatment of major depression or substance use disorder.2 However, it is currently unclear whether the aforementioned acute subjective (...) effects are necessary to bring about the observed therapeutic effects of psilocybin and other psychedelics. This uncertainty has sparked a lively—though still largely hypothetical—debate on whether psychedelics without subjective effects (“nonsubjective psychedelics” or “non-hallucinogenic psychedelics”) could still have the same therapeutic impact, or whether the acute subjective effects are in fact necessary for this impact to be fully realized.3,4,5. (shrink)

Proponents of the problem of animal suffering claim that the millions of years of apparent nonhuman animal pain and suffering provides evidence against the existence of God. Neo-Cartesianism attempts to avoid this problem mainly by denying the existence of phenomenal consciousness in nonhuman animals. However, neo-Cartesian options regarding animal minds have failed to compel many. In this essay, I explore an answer to the problem of animal suffering inspired by the medieval theologian Thomas Aquinas. Instead of focusing on phenomenal consciousness, (...) the neo-Thomistic view of animal minds focuses on self-awareness. After proposing and providing evidence for this view, I conclude that nonhuman animal suffering is not morally significant. (shrink)

Recently the intramural debate among Christians over the correct interpretation of Genesis 1 and the age of the earth has become heated between leaders of certain science-based ministries. A major point of contention revolves around the question of whether there was animal death before Adam and Eve’s first sin. Many young-earth proponents charge that if God allowed death before Adam and Eve sinned, then God would not be morally perfect. In this paper I propose and critique a logical argument from (...) these charges. First, I formulate a logical problem based on the claims of young-earth proponents. Next, I discuss several theistic interpretations of God’s moral perfection and explain how deontological and consequentialist interpretations are problematic. After this I discuss Aquinas’ interpretation of God’s moral perfection. Finally, I provide a solution to the problem of death before the fall using Aquinas’ interpretation. I conclude that it is not logically contradictory to believe that God is all-knowing, all-powerful, and all-good and that He created a world that initially contained animal death. (shrink)

The question of whether the existence of evil in the world is compatible with the existence of an all-knowing, all-powerful, all-good God has been debated for centuries. Many have addressed classical arguments from evil, and while recent scholarship in analytic philosophy of religion has produced newer formulations of the problem, most of these newer formulations rely on a conception of God that is not held by all theists. In Bringing Good Even Out of Evil: Thomism and the Problem of Evil, (...) B. Kyle Keltz defends classical theism against contemporary problems of evil through the philosophy of Thomas Aquinas and his interpreters. Keltz discusses Aquinas’s thought on God, evil, and what kind of world God would make, then turns to contemporary problems of evil and shows how they miss the mark when it comes to classical theism. Some of the newer formulations that the book considers include James Sterba’s argument from the Pauline principle, J. L. Schellenberg’s divine hiddenness argument, Stephen Law’s evil-god challenge, and Nick Trakakis’s anti-theodicy. (shrink)

The problem of animal suffering is the atheistic argument that an all-knowing, all-powerful, and all-good God would not use millions of years of animal suffering, disease, and death to form a planet for human beings. This argument has not received as much attention in the philosophical literature as other forms of the problem of evil, yet it has been increasingly touted by atheists since the time of Charles Darwin. While several theists have attempted to provide answers to the problem, they (...) disagree with each other as to which answer is correct. Also, some of these theists have given in to the problem and believe it entails that God is limited in certain ways. B. Kyle Keltz seeks to provide a classical answer to the problem of animal suffering inspired by the medieval philosopher/theologian Thomas Aquinas. In doing so, Keltz not only utilizes the wisdom of Aquinas, but also contemporary insights into non-human animal minds from contemporary philosophy and science. Keltz provides a compelling neo-Thomistic answer to the problem of animal suffering and explains why the classical God of theism would create a world that includes animal death. (shrink)

The problem of animal suffering considers whether God would allow millions of years of animal pain, disease, and death. Philosophers who debate this issue often assume that pain and suffering are evils a loving God would not allow without good reason. Moreover, a considerable amount of the debate regarding the problem of animal suffering involves whether animals are capable of experiencing pain and suffering. But this raises the question of whether pain and suffering are intrinsically evil. In this essay I (...) explore the nature of pain and suffering from a Thomistic perspective. First I briefly explain how the intrinsic values of pain and suffering are crucial regarding the problem of evil and the problem of animal suffering in particular. Next I explain the Thomistic concepts of pain and suffering and show that they do not contradict their contemporary philosophical and scientific counterparts. Afterward I determine whether pain and suffering are intrinsically evil experiences that an all-good God should refrain from causing. I conclude that pain and suffering are not intrinsically evil and that the problem of animal suffering is not a problem in addition to the problem of natural evil. (shrink)

Thomas Aquinas is often mentioned in the debate regarding best possible worlds. Some philosophers believe Aquinas’ writings entail that God must create a best possible world while most think he rejects the notion. Additionally, it is thought that Aquinas’ position falls prey to the problem of no best world. However, a closer examination of Aquinas’ metaphysical views shows that he has been misunderstood in the current debate. In this essay, I first examine some contemporary views regarding Aquinas’ thought on best (...) possible worlds. Afterward, I discuss Aquinas’ concepts of God’s goodness and God’s purpose for creating and determine their implications for his position regarding best possible worlds. Understanding these concepts helps to show why Aquinas’ position has been misrepresented. I conclude that while Aquinas does reject the popular notion of a best possible world, his arguments are not susceptible to the problem of no best world. (shrink)

BackgroundSystems medicine is the name for an assemblage of scientific strategies and practices that include bioinformatics approaches to human biology ; “big data” statistical analysis; and medical informatics tools. Whereas personalized and precision medicine involve similar analytical methods applied to genomic and medical record data, systems medicine draws on these as well as other sources of data. Given this distinction, the clinical translation of systems medicine poses a number of important ethical and epistemological challenges for researchers working to generate systems (...) medicine knowledge and clinicians working to apply it.DiscussionThis article focuses on three key challenges: First, we will discuss the conflicts in decision-making that can arise when healthcare providers committed to principles of experimental medicine or evidence-based medicine encounter individualized recommendations derived from computer algorithms. We will explore in particular whether controlled experiments, such as comparative effectiveness trials, should mediate the translation of systems medicine, or if instead individualized findings generated through “big data” approaches can be applied directly in clinical decision-making. Second, we will examine the case of the Riyadh Intensive Care Program Mortality Prediction Algorithm, pejoratively referred to as the “death computer,” to demonstrate the ethical challenges that can arise when big-data-driven scoring systems are applied in clinical contexts. We argue that the uncritical use of predictive clinical algorithms, including those envisioned for systems medicine, challenge basic understandings of the doctor-patient relationship. Third, we will build on the recent discourse on secondary findings in genomics and imaging to draw attention to the important implications of secondary findings derived from the joint analysis of data from diverse sources, including data recorded by patients in an attempt to realize their “quantified self.”SummaryThis paper examines possible ethical challenges that are likely to be raised as systems medicine to be translated into clinical medicine. These include the epistemological challenges for clinical decision-making, the use of scoring systems optimized by big data techniques and the risk that incidental and secondary findings will significantly increase. While some ethical implications remain still hypothetical we should use the opportunity to prospectively identify challenges to avoid making foreseeable mistakes when systems medicine inevitably arrives in routine care. (shrink)

What is the significance of the wicked problems framework for environmental philosophy? In response to wicked problems, environmental scientists are starting to welcome the participation of social scientists, humanists, and the creative arts. We argue that the need for interdisciplinary approaches to wicked problems opens up a number of tasks that environmental philosophers have every right to undertake. The first task is for philosophers to explore new and promising ways of initiating philosophical research through conducting collaborative learning processes on environmental (...) issues. The second task is for philosophers to recognize the value of philosophical skills in their engagements with members of other disciplines and walks of life in addressing wicked problems. The wicked problems framework should be seen as an important guide for facilitating philosophical research that is of relevance to problems like climate change and sustainable agriculture. Content Type Journal Article Category Articles Pages 1-14 DOI 10.1007/s10806-011-9344-0 Authors Paul B. Thompson, Department of Philosophy, Michigan State University, 503 S. Kedzie Hall, East Lansing, MI 48824, USA Kyle Powys Whyte, Department of Philosophy, Michigan State University, 503 S. Kedzie Hall, East Lansing, MI 48824, USA Journal Journal of Agricultural and Environmental Ethics Online ISSN 1573-322X Print ISSN 1187-7863. (shrink)

As infancy is characterized by rapid physical growth and critical periods of development, disruptions due to illness or disease reveal vulnerability associated with this period. Spinal cord injury has devastating consequences at any age, but its onset neonatally, at birth, or within the first year of life multiplies its impact. The immediate physical and physiological consequences are obvious and immense, but the effects on the typical trajectory of development are profound. Activity-based restorative therapies capitalize on activity-dependent plasticity of the neuromuscular (...) system below the lesion and when provided to children with SCI aim to improve the child’s neuromuscular capacity, health and quality of life. This is a report of an infant with a cervical SCI at birth resulting in paralysis of leg and trunk muscles and paresis of arm and hands who was enrolled in an ABRT program at 3 years of age. After 59 sessions of ABRT, the child demonstrated significant improvements in trunk control and arm function, as well as social and emotional development. Despite the chronicity of injury and low expectations for improvement with therapeutic interventions, ABRT had a positive impact on the child’s physical capacity and provided benefits across multiple developmental domains. (shrink)

We comment on the proposition “that lower temperatures and especially greater seasonal variation in temperature call for individuals and societies to adopt … a greater degree of self-control” (Van Lange et al., sect. 3, para. 4) for which we cannot find empirical support in a large data set with data-driven analyses. After providing greater nuance in our theoretical review, we suggest that Van Lange et al. revisit their model with an eye toward the social determinants of self-control.

Not to brag, but I am a hit at parties. I tend to shine in the company of new faces, oftentimes scientists who work with my spouse.

A method now popular for fixing the scopes of arguments involves a covert movement operation, named QR (for Quantifier Rule) by Robert May. May envisioned QR as a kind of adjunction operation, attaching the arguments so affected to phrases dominating that argument. From the surface representation in (1a), for instance, QR can fashion the representations in (1b) and (1c) by adjoining the object and/or subject argument to IP. (1) a. [IP Someone [VP loves everyone ]]. b. [IP everyone1 [IP someone (...) [VP loves t1 ]]]. c. [IP someone2 [IP everyone1 [IP t2 [VP loves t1 ]]]] As the representations in (1a,b) suggest, QR has syntactic consequences rather like those displayed by Topicalization, the process that derives (2b) from (2a). (shrink)

In lieu of an abstract, here is a brief excerpt of the content:What Virgil Should Have Said KYLE GERVAIS Mortem infelicem canimus famamque perennem Sidoniae praeclara ducis quae sustulit alte moenia—multum illa et furiis iactata et amore saucia, deseruit cum foedera barbarus hospes, vique deum quassa et fratris, dum conderet ensem fatiferum profugi sub pectore et iret ad umbras, arma virumque ciens magnam contundere Romam. I sing the tragic death and endless glory Of Sidon’s exiled queen, the famous walls (...) She raised on high, her wild and wounded love When savage guest betrayed his bonded word And gods and brother shook her—till she took The fateful sword he left and sought the shades To call a man in arms to topple Rome. note With thanks to Sarah Shaughnessy for the idea and advice, and to Michael Putnam, who taught me that Dido never really dies in the Aeneid. arion 28.2 fall 2020... (shrink)

Ethics isn’t a conversation exclusive to philosophers. There is value, then, in not only understanding how laypeople think about issues in ethics, but also bringing their judgments into dialogue with those of philosophers in order to make sense of agreement, disagreement, and the consequences of each. Experimental philosophers facilitate this dialogue uniquely by capturing laypeople’s judgments and analyzing them in light of philosophical theory. They have done so almost exclusively by using face valid quantitative surveys about philosophically interesting thought experiments. (...) Based on high participant support for this or that response, researchers conclude that a given theory is more or less intuitive, and in some cases that it is or isn’t true. However, such conclusions can only be drawn from quantitative survey data if one assumes those data accurately reflect laypeople’s thinking on the issues of interest, an assumption that can’t be justified by the quantitative data itself since they are potentially opaque. This is the methodological problem of experimental philosophy: experimental philosophers who use quantitative methods alone can’t sufficiently demonstrate their data to be reflective of relevant judgments/intuitions. To better explore people’s judgments on issues in ethics and to determine whether experimental philosophers are or aren’t getting what they take themselves to be getting in surveys, I recreated part of an experiment by Chituc, Henne, Sinnott-Armstrong, and De Brigard on the Kantian principle that “ought implies can”, or that whenever an agent ought to do something then it is the case that she can, and added a layer of qualitative data to it by having participants think aloud while completing the surveys and conduct a follow-up interview. With similar quantitative results to those from Chituc et al., I argue that my qualitative results 1) cast doubt on Chituc et al.’s data being reflective of many people’s judgments, especially on the more interesting questions relating to moral obligation; 2) reveal unique insights into how people think about OIC; 3) generally speak to the value of experimental philosophers using triangulation of methods in better understanding laypeople’s complex and varied thinking about questions important to ethics and beyond. Supplemental documents: Appendices A, B, C, D, and E are surveys I used in my study. Appendices C and D are derived from Chituc et al.’s publication “Blame, Not Ability, Impacts Moral ‘Ought’ Judgments for Impossible Actions: Toward an Empirical Refutation of ‘Ought’ Implies ‘Can.’” Appendix F is the recruitment flyer I distributed for my study. Appendix H is the quantitative data from my study. (shrink)

In recent work, Andrew T. Forcehimes and Robert B. Talisse correctly note that G.A. Cohen’s fact-insensitivity thesis, properly understood, is explanatory. This observation raises an important concern. If fact-insensitive principles are explanatory, then what role can they play in normative deliberations? The purpose of my paper is, in part, to address this question. Following David Miller, I indicate that on a charitable understanding of Cohen’s thesis, an explanatory principle explains a justificatory fact by completing an otherwise logically incomplete inference. As (...) a result, the explanatory role such a principle plays is inseparable from its status as a (not necessarily successful) justificatory reason. With this interpretation in hand, I then proceed to argue that Lea Ypi’s and Robert Jubb’s recent criticisms fail to undermine Cohen’s thesis, and that fact-insensitive principles, once discovered, are especially helpful for purposes of deliberation in circumstances characterized by changing and changeable feasibility constraints. (shrink)