The case (Dawson et al. 2024) describes an Institutional Review Board (IRB) chair who seeks consultation about waiving the requirement that investigators obtain prospective, informed consent for co...

Innovative practice occurs when a clinician provides something new, untested, or nonstandard to a patient in the course of clinical care, rather than as part of a research study. Commentators have noted that patients engaged in innovative practice are at significant risk of suffering harm, exploitation, or autonomy violations. By creating a pathway for harmful or nonbeneficial interventions to spread within medical practice without being subjected to rigorous scientific evaluation, innovative practice poses similar risks to the wider community of patients (...) and society as a whole. Given these concerns, how should we control and oversee innovative practice, and in particular, how should we coordinate innovative practice and clinical research? In this article, I argue that an ethical approach to overseeing innovative practice must encourage the early transition to rigorous clinical research without delaying or deferring the development of beneficial innovations or violating the autonomy rights of clinicians and their patients. (shrink)

Several philosophers have recently argued that policies aimed at reducing human fertility are a practical and morally justifiable way to mitigate the risk of dangerous climate change. There is a powerful objection to such “population engineering” proposals: even if drastic fertility reductions are needed to prevent dangerous climate change, implementing those reductions would wreak havoc on the global economy, which would seriously undermine international antipoverty efforts. In this article, we articulate this economic objection to population engineering and show how it (...) fails. We argue, first, that the economic objection paints an inaccurate picture of the complicated relationship between demographic change and economic growth, and second, that any untoward economic effects of fertility reduction can be mitigated with additional policies. Specifically, we argue that supplementing fertility reduction with policies that facilitate the emigration of younger people from developing nations to developed nations could allow for both global reductions in GHG emissions and continued economic stability. Further, we show that moral arguments against such unprecedented increases in immigration are unsuccessful. We conclude that population engineering is a practical and morally justifiable tool for addressing the twin evils of climate change and global poverty. (shrink)

The Procreation Asymmetry holds that we have strong moral reasons not to create miserable people for their own sakes, but no moral reasons to create happy people for their own sakes. To defend this conjunction against an argument that it leads to inconsistency, I show how recognizing ‘creation’ as a temporally extended process allows us to revise the conjuncts in a way that preserves their intuitive force. This defense of the Procreation Asymmetry is preferable to others because it does not (...) require us to take on controversial metaphysical or metaethical commitments – in other words, it has the theoretical virtue of portability. (shrink)

Many contemporary ethical debates turn on claims about the nature and extent of our alleged procreative moral rights: moral rights to procreate or not to procreate as we choose. In this article, I argue that there are no procreative moral rights, in that generally we do not have a distinctive moral right to procreate or not to procreate as we choose. However, interference with our procreative choices usually violates our nonprocreative moral rights, such as our moral rights to bodily autonomy (...) or to privacy. My argument presents hypothetical cases in which a state interferes with a person's procreative choices in order to promote aggregate social welfare, but this interference does not violate any of the person's nonprocreative moral rights. These cases not only undermine frequently made claims that widely recognized nonprocreative moral rights entail procreative moral rights, they also challenge the intuitively plausible claim that interference with our procreative choices as such violates our moral rights. What at first appear to be substantive moral rights are in fact a kind of illusion created by the frequent overlap of other rights, but lacking in substance beyond that overlap. While this argument against the existence of procreative moral rights has substantive implications for ongoing debates in reproductive ethics, I ultimately suggest that it is consistent with a progressive approach to reproductive justice. (shrink)

This Ideas and Opinions article revisits an argument from Judith Jarvis Thomson in her essay “A Defense of Abortion” that abortion can be an ethical choice even if we assume that fetuses have full moral personhood and moral rights. The authors examine the implications of laws that require a pregnant person to care for another with their body and what other impositions states may also require of citizens to care for others.

Although researchers generally take great care to ensure that human subjects do not suffer very serious harms from their involvement in research, the situation is different for nonhuman animal subjects. Significant progress has been made in reducing unnecessary animal suffering in research, yet researchers still inflict severe pain and distress on tens of thousands of animals every year for scientific purposes. Some bioethicists, scientists, and animal welfare advocates argue for placing an upper limit on the suffering researchers may impose on (...) animal subjects, with rare exceptions for research that promises critical social benefits. In this article, I argue against such an upper limit on harm on the grounds that researchers often can compensate animal subjects for their suffering, even severe and long-lasting suffering. If animal subjects receive adequate compensation for the harms they suffer, then there is no general limit on how much suffering researchers may impose on them for scientific purposes. (shrink)

Eyal et al have recently argued that researchers should consider conducting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human challenge studies to hasten vaccine development. We have conducted (J. L.) and overseen (L. D.) human challenge studies and agree that they can be useful in developing anti-infective agents. We also agree that adults can autonomously choose to undergo risks with no prospect of direct benefit to themselves. However, we disagree that SARS-CoV-2 challenge studies are ethically appropriate at this time, for (...) 3 reasons: (1) current scientific knowledge of SARS-CoV-2 infection is insufficient to manage risks; (2) autonomous decision making, while necessary, does not override concerns about risk; and (3) undertaking challenge studies now would imperil confidence in the research enterprise, potentially undermining the global response to the coronavirus disease 2019 (COVID-19) pandemic. (shrink)

The case describes researchers who are seeking ethics guidance on communicating with participants in a phase-1 COVD-19 vaccine trial about FDA-authorized COVID-19 vaccines (Wilfond, Duenas, and Johnson 2023). The researchers want help choosing among three options they have identified for encouraging participants to obtain one of the authorized vaccines. We argue that research ethics consultants should consider going beyond this question to address another ethics concern the researchers might have overlooked.

One of the Belmont Report’s most important contributions was the clear and serviceable distinction it drew between standard medical practice and biomedical research. A less well-known achievement of the Report was its conceptualization of innovative practice, a type of medical practice that is often mistaken for research because it is new, untested, or experimental. Although the discussion of innovative practice in Belmont is brief and somewhat cryptic, this does not reflect the significant progress its authors made in understanding innovative practice (...) and the distinctive ethical issues it raises. This article explores the history and broader context of Belmont’s conception of innovative practice, its strengths and weaknesses, and its contemporary relevance for scholars working in bioethics and health policy. While this conception of innovative practice deserves our attention, it is inherently limited in some important ways. (shrink)

Innovative practice involves medical interventions that deviate from standard practice in significant ways. For many patients, innovative practice offers the best chance of successful treatment. Because little is known about most innovative treatments, clinicians who engage in innovative practice might consider including extra procedures, such as scans or blood draws, to gather information about the innovation. Such information-gathering interventions can yield valuable information for modifying the innovation to benefit future patients and for designing scientific studies of the innovation. However, existing (...) guidelines do not say when or whether it is appropriate to add potentially risky information-gathering interventions for these purposes. As a result, clinicians may assume that information-gathering interventions are ethically inappropriate and should not be used in innovative practice. This assumption can lead to seriously negative consequences, such as increasing the likelihood that harmful or ineffective innovations will be adopted and creating new barriers to the development of genuinely beneficial treatments. We argue that health care institutions need to promote the responsible use of information-gathering interventions as an adjunct to innovative practice, and that these interventions are not clinical research and should not be subject to research oversight. (shrink)

Contrary to political and philosophical consensus, we argue that the threats posed by climate change justify population engineering, the intentional manipulation of the size and structure of human populations. Specifically, we defend three types of policies aimed at reducing fertility rates: choice enhancement, preference adjustment, and incentivization. While few object to the first type of policy, the latter two are generally rejected because of their potential for coercion or morally objectionable manipulation. We argue that forms of each policy type are (...) pragmatically and morally justified tools for preventing the harms of global climate change. (shrink)

Parental Obligations and Bioethics: The Duties of a Creator collects and supplements Bernard G. Prusak’s work on the ethics of procreation and parenthood, and applies his unique theoretical approach to related issues in bioethics and social philosophy. In this review, I’ll first summarize what I take to be the argumentative core of the book, and then offer a brief critical assessment.

Each of the 13 articles in this collection wrestles with intricate metaphysical and moral aspects of the widespread belief that a thing’s potential—what it could, would, might, or will be, but isn’t yet—matters for how we should treat that thing. As John Lizza explains in his lucid introduction, the articles are grouped into three parts according to their aims and theoretical constraints. In this review, I briefly summarize and offer some critical discussion of each part.

The Routledge Handbook of the Philosophy of Childhood and Children is an impressive collection of original essays on conceptual and normative issues related to the first (post-natal) phases of human life. As co-editor Anca Gheaus notes in her introduction to the collection, philosophers’ historical inattention to these issues is “puzzling”, given the importance of childhood and children for both individual and societal flourishing (p. 1). Attentive readers will be even more puzzled by this fact, given the variety of interesting, challenging (...) questions raised by the collection’s 44 contributors. It is even more striking that despite the size and scope of the collection, most of its essays are introductory in nature, primarily orienting readers to ongoing philosophical debates or noting topics for future investigation. The very existence of such a collection makes a strong case that the philosophy of childhood and children is and will continue to be a worthwhile endeavor. (shrink)

This chapter formulates a rational uniqueness principle holding that those who are epistemic peers on a proposition, in that they know that they share all rational considerations concerning the truth of the proposition, cannot be justified in having different attitudes toward it. It then argues against the principle, primarily on the grounds that such peers may rationally regard themselves as differing in their basis for rational belief, or their evidence, on the topic. The rationality of their differing perspectives can justify (...) having different attitudes toward the disputed proposition. (shrink)

Peter Lamarque, in chapter 4 of his 2010 book Work and Object, argues that certain artworks, like musical scores and literary texts, are such that there can be no forgeries of them that purport to be of an actually existing work—what Lamarque calls “referential forgeries”. Lamarque motivates this claim via appeal to another distinction, first made by Goodman, between “allographic” and “autographic” artworks. This article will evaluate Lamarque’s argument that allographic literary works are unable to be referentially forged and will (...) find them wanting. In so doing, the distinction between allographic and autographic artworks (and therefore artforms) will be called into question. In section I, I characterize referential forgery and Lamarque’s definition of allographic and autographic artforms. Section II critically examines Lamarque’s argument against the possibility of referential forgery in allographic artforms. Section III offers a case where it appears that a putatively allographic text’s type membership is sensitive to facts about its causal-intentional provenance. This case serves as pretext for Section IV’s identification of this causal-intentional relation with the sanctioning relation as formulated by Sherri Irvin. On the basis of considerations treated in sections I through IV, section V questions the tenability of the allographic/autographic distinction. -/- . (shrink)

What makes democracy valuable? One traditional answer holds that participating in democratic self-government amounts to a kind of autonomy: it enables citizens to be the authors of their political affairs. Many contemporary philosophers, however, are skeptical. We are autonomous, they argue, when important features of our lives are up to us, but in a democracy we merely have a say in a process of collective choice. In this paper, we defend the possibility of democratic autonomy, by advancing a conception of (...) it which is impervious to this objection. At the core of our account is the idea of joint authorship. You are a joint author of something when that thing expresses your joint intentions. Democracy may not make any one of us sole author of our political affairs, but it can make us their joint authors. It is in such joint authorship, we claim, that the intrinsic value of democratic self-government consists. (shrink)

Several contemporary philosophers have argued that democracy earns its moral keep in part by rendering political authority compatible with social or relational equality. In a recent article in this journal, Alexander Motchoulski examines these relational egalitarian defenses of democracy, finds the standard approach wanting, and advances an alternative. The standard approach depends on the claim that inequality of political power constitutes status inequality (the ‘constitutive claim’). Motchoulski rejects this claim on the basis of a theory of social status: once you (...) see what social status is, Motchoulski thinks, the constitutive claim is a non-starter. In its place, Motchoulski suggests that relational egalitarians can and should content themselves with a defense of democratic institutions on the basis of a causal-instrumental link between equality of political power and equality of social relations. In this reply, I advance three main claims. First, relational egalitarians have good reason to hope for a defense of the constitutive claim, since that claim is required if relational equality is to vindicate the intrinsic value of democracy. Second, Motchoulski’s argument against the constitutive claim fails, because it depends on conflating one species of social status for the genus as a whole. Finally, I argue that the constitutive claim is trivially true for one kind of status, namely de facto authority, but, since equality of that kind of status is not intrinsically valuable, this does not amount to a defense of the intrinsic value of democracy. (shrink)

Organizations are making massive investments in artificial intelligence, and recent demonstrations and achievements highlight the immense potential for AI to improve organizational and human welfare. Yet realizing the potential of AI necessitates a better understanding of the various ethical issues involved with deciding to use AI, training and maintaining it, and allowing it to make decisions that have moral consequences. People want organizations using AI and the AI systems themselves to behave ethically, but ethical behavior means different things to different (...) people, and many ethical dilemmas require trade-offs such that no course of action is universally considered ethical. How should organizations using AI—and the AI itself—process ethical dilemmas where humans disagree on the morally right course of action? Though a variety of ethical AI frameworks have been suggested, these approaches do not adequately address how people make ethical evaluations of AI systems or how to incorporate the fundamental disagreements people have regarding what is and is not ethical behavior. Drawing on moral foundations theory, we theorize that a person will perceive an organization’s use of AI, its data procedures, and the resulting AI decisions as ethical to the extent that those decisions resonate with the person’s moral foundations. Since people hold diverse moral foundations, this highlights the crucial need to consider individual moral differences at multiple levels of AI. We discuss several unresolved issues and suggest potential approaches for thinking about conflicts in moral judgments concerning AI. (shrink)

Philosophy as a way of life (PWOL) places investigations of value, meaning, and the good life at the center of philosophical investigation, especially of one’s own life. This essay argues that PWOL is compatible with general introductory philosophy courses, further arguing that PWOL‐based general introductions have several philosophical and pedagogical benefits. These include the ease with which high‐impact practices, situated skill development, and students’ ability to “think like a disciplinarian” may be incorporated into such courses, relative to more traditional introductory (...) courses, as well as the demonstration of philosophy’s value to students by explicitly tying philosophical investigation to students’ own lives. (shrink)

A survey of the recent literature suggests that physicians should engage religious patients on religious grounds when the patient cites religious considerations for a medical decision. We offer two arguments that physicians ought to avoid engaging patients in this manner. The first is the Public Reason Argument. We explain why physicians are relevantly akin to public officials. This suggests that it is not the physician’s proper role to engage in religious deliberation. This is because the public character of a physician’s (...) role binds him/her to public reason, which precludes the use of religious considerations. The second argument is the Fiduciary Argument. We show that the patient-physician relationship is a fiduciary relationship, which suggests that the patient has the clinical expectation that physicians limit themselves to medical considerations. Since engaging in religious deliberations lies outside this set of considerations, such engagement undermines trust and therefore damages the patient-physician relationship. (shrink)

The prefrontal cortex has long been suspected to play an important role in cognitive control, in the ability to orchestrate thought and action in accordance with internal goals. Its neural basis, however, has remained a mystery. Here, we propose that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them. They provide bias signals to other brain structures whose net effect is to guide the flow of (...) activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task. We review neurophysiological, neurobiological, neuroimaging, and computational studies that support this theory and discuss its implications as well as further issues to be addressed. (shrink)

Extended Reality (XR) and Large Language Model (LLM) technologies have the potential to significantly influence higher education practices and pedagogy in the coming years. As these emerging technologies reshape the educational landscape, it is crucial for educators and higher education professionals to understand their implications and make informed policy decisions for both individual courses and universities as a whole. -/- This paper has two parts. In the first half, we give an overview of XR technologies and their potential future role (...) in higher education. Then, we discuss the benefits and challenges of adopting and integrating XR technologies into higher education settings. Finally, we offer recommendations for educators, administrators, and policymakers on how to approach the adoption of this set of technologies and set institutional policy to take advantage of its benefits while minimizing its potential negative consequences. -/- In the paper’s second half, we discuss LLMs - specifically Generative Pre-trained Transformers (GPTs). Again, we provide an overview of this rapidly developing technology and examine its unprecedented and potentially disruptive impact on higher education pedagogy. We delve into the benefits and limitations of GPTs, highlighting the pedagogical and ethical challenges they may pose. Finally, we present actionable recommendations for instructors and administrators at both the course level and the university-wide level to guide policy decisions concerning these transformative technologies. (shrink)

How do you tell what’s right from what’s wrong? Can you always? What’s the difference between deduction, induction, and abduction? What are the best techniques for making an argument logically sound? In this fascinating little book, the smallest on its subject ever produced, philosopher Earl Fontainelle explores the ancient art of discursive Logic and demonstrates some of the techniques that have long been used to triumph over the debates and deceptions that assail us every day. Filled with helpful examples (...) of good and bad reasoning, Logic is an invaluable introduction to a defining human characteristic. (shrink)

One of the most popular arguments in favor of dualism is the zombie-conceivability argument. It is often argued that the possibility of zombies would entail that mental properties are epiphenomenal. This paper attempts to defuse the argument, offering a model of dualist mental causation which can serve as a basis for a modified, interactionist-friendly zombie argument.

This essay takes up a challenge recently posed by Graham Oppy: to clearly express, in premise-conclusion form, Hegel's version of the ontological argument. In addition to employing this format, it seeks to supplement existing treatments by locating a core component of Hegel's argument in a slightly different place than is common. Whereas some prominent recent treatments (Williams, Bubbio, Melechar) focus on Hegel's definition of the Absolute as the Concept, from the third part of his Science of Logic (the Doctrine of (...) the Concept), mine focuses on earlier definitions from the first (the Doctrine of Being). As I hope to show, there are even more resources in Hegel's Logic for an ontological argument than those emphasized in recent treatments: the concept, the Idea, etc. Already in the first third of the Logic, we find a compelling response to a famous Kantian counter-argument to the ontological proof. The counter-argument is summed up in the phrase ‘existence [Sein] is not a real predicate’. Hence, Hegel's response as I interpret it will take the form of a competing analysis of Being, a Lehre vom Sein (Doctrine of Being). What do we learn when we put the ontology back into Hegel's ontological argument? That Being is neither predicate, nor subject, nor copula, but a monist (or ‘infinite’) category. The larger importance of this exercise to our understanding of Hegel's thought lies in the way it clarifies his profound debt to even non-idealist conceptions of God, such as the one espoused by Spinoza. (shrink)

Aulisio and Arora argue that the moral significance of value imposition explains the moral distinction between traditional conscientious objection and non-traditional conscientious objection. The former objects to directly performing actions, whereas the latter objects to indirectly assisting actions on the grounds that indirectly assisting makes the actor morally complicit. Examples of non-traditional conscientious objection include objections to the duty to refer. Typically, we expect physicians who object to a practice to refer, but the non-traditional conscientious objector physician refuses to refer. (...) Aulisio and Arora argue that physicians have a duty to refer because refusing to do so violates the patient’s values. While we agree with Aulisio and Arora’s conclusions, we argue value imposition cannot adequately explain the moral difference between traditional conscientious objection and non-traditional conscientious objection. Treating autonomy as the freedom to live in accordance with one’s values, as Aulisio and Arora do, is a departure from traditional liberal conceptions of autonomy and consequently fails to explain the moral difference between the two kinds of objection. We outline how a traditional liberal understanding of autonomy would help in this regard, and we make two additional arguments—one that maintains that non-traditional conscientious objection undermines society’s autonomy, and another that maintains that it undermines the physician-patient relationship—to establish why physicians have a duty to refer. (shrink)

Abstract: This paper develops and advocates a rule for assigning self-locating credences in quantum branching scenarios, called Indexed Branch-Counting. It is argued that Indexed Branch-Counting can be justified on both accuracy-theoretic grounds and on the grounds that it satisfies a requirement of exchangeability for probability assignments. Since Indexed Branch-Counting diverges from the Born Rule, this poses trouble for Everettian approaches to probability. The paper also addresses a common argument against branch-counting, namely that the rule is incoherent in light of putative (...) vagueness in the number of branches. Finally, the paper addresses a recent proposal from Simon Saunders that aims to reconcile branch-counting with the Born Rule, arguing that the proposal faces challenges. (shrink)

Reductive accounts of the direction of time are often paired with Humean accounts of laws, while non-reductive accounts of time are often paired with anti-Humean accounts of laws. The traditional pairing of views has recently come under question. This paper aims to clarify what sorts of anti-Humean views motivate anti-reductionism about the direction of time. It is argued that those who think (i) that the laws are metaphysically fundamental, and (ii) that the laws contain time-asymmetric contents, should treat the arrow (...) of time as metaphysically fundamental. (shrink)

Diverse and dynamic societies face a problem of social control. Institutions of social control, of which the police are a part, are a necessary part of just and legitimate governance. But in our non-ideal world they are also responsible for injustices of their own. This project raises questions of political philosophy as they apply to the professional police agency. It begins by constructing an inchoate, but mainstream view about just policing, legalism, according to which police power is justified by the (...) criminal code, and just policing is just the faithful enforcement of law. This view is undermined by the practical realities of policing, which involves widespread and unavoidable police discretion. It then develops an account of just and legitimate police discretion, including principles of proportionality, liberal neutrality, and democratic responsiveness. This sheds lights on controversial police tactics, order maintenance initiatives, and community policing strategies. This account also informs the just institutional arrangement of police powers, informing ongoing debates about police reform and abolition. (shrink)

Previous research has shown that the UK has low levels of financial literacy by international standards, particularly among those in lower socio-economic groups. This may have an impact upon young people, with social inequalities in financial attitudes, behaviours and skills perpetuating across generations. Using parent-child linked survey data from 3,745 UK families, we find sizeable socio-economic inequalities in young people’s financial capabilities, aspects of their mindset, and their financial behaviours. Sizeable differences are also observed in the financial education that socio-economically (...) advantaged and disadvantaged children receive at school, and how they interact with their parents about money. Parental interactions can account for part of the socio-economic gap in money confidence, money management, financial connections, and financial behaviours, but less so in boosting financial abilities. However, we find no evidence of differences in financial education in schools driving differences in young people’s financial capabilities. (shrink)

Probability theory promises to deliver an exact and unified foundation for inquiry in epistemology and philosophy of science. But philosophy of religion is also fertile ground for the application of probabilistic thinking. This volume presents original contributions from twelve contemporary researchers, both established and emerging, to offer a representative sample of the work currently being carried out in this potentially rich field of inquiry. Grouped into five parts, the chapters span a broad range of traditional issues in religious epistemology. The (...) first three parts discuss the evidential impact of various considerations that have been brought to bear on the question of the existence of God. These include witness reports of the occurrence of miraculous events, the existence of complex biological adaptations, the apparent 'fine-tuning' for life of various physical constants and the existence of seemingly unnecessary evil. The fourth part addresses a number of issues raised by Pascal's famous pragmatic argument for theistic belief. A final part offers probabilistic perspectives on the rationality of faith and the epistemic significance of religious disagreement. (shrink)

It is well known that classical, aka ‘sharp’, Bayesian decision theory, which models belief states as single probability functions, faces a number of serious difficulties with respect to its handling of agnosticism. These difficulties have led to the increasing popularity of so-called ‘imprecise’ models of decision-making, which represent belief states as sets of probability functions. In a recent paper, however, Adam Elga has argued in favour of a putative normative principle of sequential choice that he claims to be borne out (...) by the sharp model but not by any promising incarnation of its imprecise counterpart. After first pointing out that Elga has fallen short of establishing that his principle is indeed uniquely borne out by the sharp model, I cast aspersions on its plausibility. I show that a slight weakening of the principle is satisfied by at least one, but interestingly not all, varieties of the imprecise model and point out that Elga has failed to motivate his stronger commitment. (shrink)

This paper applies the Klein Group form used by Rosalind Krauss in her essay, "Sculpture in the Expanded Field", to the field of ruins. The opposition utilized to create the ruin Klein Group is the opposition between vanished and intact. The paper proceeds by classifying and discussing each of the possibilities opened up by the expanded field: ruins (not-vanished ; not-intact), consecrated sites (vanished ; not-vanished), ruin-reproduction (vanished ; intact), and finally the "necroaesthetical ruin" (intact ; not-intact). The expanded field (...) and the political and aesthetic implications thereof are discussed primarily in conversation with Paolo Virno's "Deja Vu and the End of History," as well as Achille Mbembe's "Necropolitics" and Andreas Huyssen's "Nostalgia for Ruins.”. (shrink)

When behaviors assemble into combinations, then synergies have a central role in the discovery of productive patterns of behavior. In our view—what we call the Synergy Emergence Principle (SEP)—synergies are dynamic attractors, drawing interactions toward greater returns as they happen, in the moment. This Principle offers an alternative to the two conventionally acknowledged routes to discovery: directed problem solving, involving forethought and planning; and the complete randomness of trial and error. Natural selection has a role in the process, in humans (...) favoring the maintenance and improvement of certain key underlying capabilities, such as prosocial helping and episodic foresight, but selection is not required for discovery by synergy (which occurs too rapidly for selection anyway). Here we discuss the consequences of the SEP for the evolution in humans of key synergies such as tool usage and interactions that reward cooperation, show how discovery by synergy and the selection of synergy-supporting abilities formed a positive feedback loop, and show how synergies can combine, forming clusters and packages that are the core of institutions and cultures. Finally, clusters and packages represent an intermediate level of organization above the individual and below whole society, with consequences for our understanding of the major transitions in evolution. (shrink)