Varieties of Explanation

For synergistic interactions between humans and artificial intelligence (AI) systems, AI outputs often need to be explainable to people. Explainable AI (XAI) systems are commonly tested in human user studies. However, whether XAI researchers consider potential cultural differences in human explanatory needs remains unexplored. We highlight psychological research that found significant differences in human explanations between many people from Western, commonly individualist countries and people from non-Western, often collectivist countries. We argue that XAI research currently overlooks these variations and that (...) many popular XAI designs implicitly and problematically assume that Western explanatory needs are shared cross-culturally. Additionally, we systematically reviewed over 200 XAI user studies and found that most studies did not consider relevant cultural variations, sampled only Western populations, but drew conclusions about human-XAI interactions more generally. We also analyzed over 30 literature reviews of XAI studies. Most reviews did not mention cultural differences in explanatory needs or flag overly broad cross-cultural extrapolations of XAI user study results. Combined, our analyses provide evidence of a cultural bias toward Western populations in XAI research, highlighting an important knowledge gap regarding how culturally diverse users may respond to widely used XAI systems that future work can and should address. (shrink)

Dissertation Prospectus. Exploring the limits of New Mechanism as a general theory of scientific explanation, limiting its scope and proposing constraints.

Distinctively mathematical explanations (DMEs) explain natural phenomena primarily by appeal to mathematical facts. One important question is whether there can be an ontic account of DME. An ontic account of DME would treat the explananda and explanantia of DMEs as ontic structures and the explanatory relation between them as an ontic relation (e.g., Pincock 2015, Povich 2021). Here I present a conventionalist account of DME, defend it against objections, and argue that it should be considered ontic. Notably, if indeed it (...) is ontic, the conventionalist account seems to avoid a convincing objection to other ontic accounts (Kuorikoski 2021). (shrink)

Ground is all the rage in contemporary metaphysics. But what is its nature? Some metaphysicians defend what we could call, following Skiles and Trogdon (2021), the inheritance view: it is because constitutive forms of metaphysical explanation are such-and-such that we should believe that ground is so-and-so. However, many putative instances of inheritance are not primarily motivated by scientific considerations. This limitation is harmless if one thinks that ground and science are best kept apart. Contrary to this view, we believe that (...) ground is a highly serviceable tool for investigating metaphysical areas of science. In this paper, we defend a naturalistic version of the inheritance view which takes constitutive scientific explanation as a better guide to ground. After illustrating the approach and its merits, we discuss some implications of the emerging scientific conception for the theory of ground at large. (shrink)

Recent years have seen growing interest in modifying interventionist accounts of causal explanation in order to characterise noncausal explanation. However, one surprising element of such accounts is that they have typically jettisoned the core feature of interventionism: interventions. Indeed, the prevailing opinion within the philosophy of science literature suggests that interventions exclusively demarcate causal relationships. This position is so prevalent that, until now, no one has even thought to name it. We call it “intervention puritanism” (I-puritanism, for short). In this (...) paper, we mount the first sustained defence of the idea that there are distinctively noncausal explanations which can be characterized in terms of possible interventions; a position we call “intervention liberalism” (I-liberalism, for short). While many have followed James Woodward (2003) in committing to I-puritanism, we trace support for I-liberalism back to the work of Jaegwon Kim (1974). Furthermore, we analyse two recent sources of scepticism regarding I-liberalism: debate surrounding mechanistic constitution; and attempts to provide a monistic account of explanation. We show that neither literature provides compelling reasons for adopting I-puritanism. Finally, we present a novel taxonomy of available positions upon the role of possible interventions in explanation: weak causal imperialism; strong causal imperialism; monist intervention puritanism; pluralist intervention puritanism; monist intervention liberalism; and finally, the specific position defended in this paper, pluralist intervention liberalism. (shrink)

Some theorists of normative explanation argue that we can make sense of debates between first-order moral theories such as consequentialism and its rivals only if we understand their explanations of why the right acts are right and the wrong acts are wrong as generative (e.g. grounding) explanations. Others argue that the standard form of normative explanation is, instead, some kind of unification. Neither sort of explanatory monism can account for all the explanations of particular moral facts that moral theorists seek (...) to state and defend. This paper argues that we can do better if we accept normative explanatory pluralism, the view that at least some particular explananda in normative inquiry have more than one type of correct complete explanation. Such pluralism is supported by what goes on in actual moral inquiry, parallels an independently plausible form of pluralism about scientific explanation, and can offer principled responses to central objections. (shrink)

The philosophical literature on scientific explanation in neuroscience has been dominated by the idea of mechanisms. The mechanist philosophers often claim that neuroscience is in the business of finding mechanisms. This view has been challenged in numerous ways by showing that there are other successful and widespread explanatory strategies in neuroscience. However, the empirical evidence for all these claims was hitherto lacking. Empirical evidence about the pervasiveness and uses of various explanatory strategies in neuroscience is particularly needed because examples and (...) case studies that are used to illustrate philosophical claims so far tend to be hand-picked. The risk of confirmation bias is therefore considerable: when looking for white swans, all one finds is that swans are white. The more systematic quantitative and qualitative bibliometric study of a large body of relevant literature that we present in this paper can put such claims into perspective. Using bibliometric tools, we identify the typical linguistic patterns used in the alleged mechanistic, dynamical, and topological explanations in the literature, their preponderance and how they change over time. Our findings show abundant use of mechanistic language, but also the presence of a significant neuroscience literature using topological and dynamical explanatory language, which grows over time and increasingly differentiates from each other and from mechanistic explanations. (shrink)

In Molière’s comedy The Imaginary Invalid a doctor “explains” that opium reliably induces sleep because it has a “dormitive virtue.” Molière intended this to be a satirical play on the use of opaque scholastic concepts in medicine, and since then the phrase “dormitive virtue” has become a byword for explanatory failure. However, contemporary work on the metaphysics of grounding and dispositions appears to permit explanations with a strikingly similar structure. In this paper I explore competing verdicts on dormitive virtue explanation, (...) using a model of explanation I call Contextualist Pluralist Non-Realist Backing, or CPN Backing. I show that CPN Backing illuminates the puzzle about dormitive virtue explanation, shows what is required for a resolution, and makes sense of conflicting responses to this case. (shrink)

Some how-possibly explanations have epistemic value because they are epistemically possible; we cannot rule out their truth. One paradoxical implication of that proposal is that epistemic value may be obtained from mere ignorance. For the less we know, then the more is epistemically possible. This chapter examines a particular class of problematic epistemically possible how-possibly explanations, viz. *epistemically opaque* how-possibly explanations. Those are how-possibly explanations justified by an epistemically opaque process. How could epistemically opaque how-possibly explanations have epistemic value if (...) they result from a process about which we lack knowledge or understanding? This chapter proposes three different strategies to salvage epistemic value from epistemic opacity, namely salvaging value from 1) functional transparency, 2) modal operator interpretation, and 3) pursuitworthiness. It illustrates using cases from deep neural network modeling. (shrink)

One of the main worries with machine learning model opacity is that we cannot know enough about how the model works to fully understand the decisions they make. But how much is model opacity really a problem? This chapter argues that the problem of machine learning model opacity is entangled with non-epistemic values. The chapter considers three different stages of the machine learning modeling process that corresponds to understanding phenomena: (i) model acceptance and linking the model to the phenomenon, (ii) (...) explanation, and (iii) attributions of understanding. At each of these stages, non-epistemic values can, in part, determine how much machine learning model opacity poses a problem. (shrink)

Philosophers pursue a number of different explanatory projects when explaining various sorts of normative phenomena. This chapter takes some steps towards understanding this variety. I lay some general ground about explanation. I describe some key axes of debate about explanations that first-order normative inquiry typically seeks to state and defend. And I briefly discuss how two other sorts of normative explanation that seem more concerned with the foundations of normative domains like ethics and practical reason might be understood and how (...) they relate to first-order normative explanations. (shrink)

Recent years have seen increasing interest in interventionist analyses of metaphysical explanation. One area where interventionism traditionally shines, is in providing an account of explanatory depth; the sense in which explanation comes in degrees. However, the literature on metaphysical explanation has left the notion of depth almost entirely unexplored. In this paper I shall attempt to rectify this oversight by motivating an interventionist analysis of metaphysical explanatory depth (MED), in terms of the range of interventions under which a metaphysically explanatory (...) generalization remains invariant. After elucidating the notion through a toy-example, I demonstrate the important work which MED can perform in characterizing debate within contemporary metaphysics. Focusing upon rival approaches to explaining the identity and distinctness of concrete objects, I argue that the progress achieved in this debate can be characterized in terms of increasing explanatory depth. Having made an initial case for the utility of MED, I then turn this analysis to the metaphysics of explanation itself. By adopting an interventionist framework with respect to MED, I will show that we can assess the depth of competing theories of explanation. This application has two interesting results: first, it suggests that an interventionist analysis of explanation provides deeper explanations of the connection between explanans and explanandum than rival accounts; and second, it suggests that explanations provided by interventionism become deeper still, if one accepts that this methodology ranges over metaphysical, as well as causal, instances. (shrink)

[This paper is available as open access from the publisher.] Normative theories aim to explain why things have the normative features they have. This paper argues that, contrary to some plausible existing views, one important kind of normative explanations which first-order normative theories aim to formulate and defend can fail to transmit downward along chains of metaphysical determination of normative facts by non-normative facts. Normative explanation is plausibly subject to a kind of a justification condition whose satisfaction may fail to (...) transmit along the relevant kind of metaphysical hierarchy. A broader aim of the paper is to contribute to systematic theorizing about normative explanation: whereas there has been a great deal of work on scientific explanation, there has been little by way of systematic exploration of what sort of explanations normative theories aim to formulate and defend. (shrink)

This paper offers a new account of metaphysical explanation. The account is modelled on Kitcher’s unificationist approach to scientific explanation. We begin, in Sect. 2, by briefly introducing the notion of metaphysical explanation and outlining the target of analysis. After that, we introduce a unificationist account of metaphysical explanation before arguing that such an account is capable of capturing four core features of metaphysical explanations: irreflexivity, non-monotonicity, asymmetry and relevance. Since the unificationist theory of metaphysical explanation inherits irreflexivity and non-monotonicity (...) directly from the unificationist theory of scientific explanation that underwrites it, we focus on demonstrating how the account can secure asymmetry and relevance. (shrink)

This paper explores the practice of explanation by status, in which a truth with a certain status is supposed to be explained by its having that status. It first investigates whether such explanations are possible. Having found existing accounts of the practice wanting, it then argues for a novel account of explanation by status as empty-base explanation. The latter notion captures a certain limiting case of ordinary explanation so that according to the empty-base account, explanation by status can be fruitfully (...) understood as a corresponding limiting case of ordinary explanation. One way in which the empty-base account is argued to be superior to other treatments of explanation by status is that it allows for a principled assessment of the possibility of particular kinds of explanation by status. Thus, one result of the present discussion is that explanation by essential status and status as a law are possible, while explanation by merely necessary status is not. (shrink)

Although clinical understandings of self-injury, the deliberate mutilation of body tissue, have developed significantly since the phenomenon was first studied, the predominant stereotype of who self-injures is still White, teenage girls.1 White girls as well as White women are, indeed, at risk for SI, and sociocultural explanations appealing to oppressive socialization—particularly the influence of Western beauty norms—have been offered to explain their high rates of SI. Yet evidence exists to challenge this conception that SI is exclusively a White, female issue: (...) Black women, South... (shrink)

Philippe Huneman has recently questioned the widespread application of mechanistic models of scientific explanation based on the existence of structural explanations, i.e. explanations that account for the phenomenon to be explained in virtue of the mathematical properties of the system where the phenomenon obtains, rather than in terms of the mechanisms that causally produce the phenomenon. Structural explanations are very diverse, including cases like explanations in terms of bowtie structures, in terms of the topological properties of the system, or in (...) terms of equilibrium. The role of mathematics in bowtie structured systems and in topologically constrained systems has recently been examined in different papers. However, the specific role that mathematical properties play in equilibrium explanations requires further examination, as different authors defend different interpretations, some of them closer to the new-mechanistic approach than to the structural model advocated by Huneman. In this paper, we cover this gap by investigating the explanatory role that mathematics play in Blaser and Kirschner’s nested equilibrium model of the stability of persistent long-term human-microbe associations. We argue that their model is explanatory because: i) it provides a mathematical structure in the form of a set of differential equations that together satisfy an ESS; ii) that the nested nature of the ESSs makes the explanation of host-microbe persistent associations robust to any perturbation; iii) that this is so because the properties of the ESS directly mirror the properties of the biological system in a non-causal way. The combination of these three theses make equilibrium explanations look more similar to structural explanations than to causal-mechanistic explanation. (shrink)

This paper examines the inferential framework employed by Palaeolithic cognitive archaeologists, using the work of Wynn and Coolidge as a case study. I begin by distinguishing minimal-capacity inferences from cognitive-transition inferences. Minimal-capacity inferences attempt to infer the cognitive prerequisites required for the production of a technology. Cognitive-transition inferences use transitions in technological complexity to infer transitions in cognitive evolution. I argue that cognitive archaeology has typically used cognitive-transition inferences informed by minimal-capacity inferences, and that this reflects a tendency to favour (...) cognitive explanations for transitions in technological complexity. Next I look at two alternative explanations for transitions in technological complexity: the demographic hypothesis and the environmental hypothesis. This presents us with a dilemma: either reject these alternative explanations or reject traditional cognitive-transition inferences. Rejecting the former is unappealing as there is strong evidence that demographic and environmental influences play some causal role in technological transitions. Rejecting the latter is unappealing as it means abandoning the idea that technological transitions tell us anything about transitions in hominin cognitive evolution. I finish by briefly outlining some conceptual tools from the philosophical literature that might help shed some light on the problem. (shrink)

The aim of this paper is to explore the ways in which Axiomatic Reconstructions of Quantum Theory in terms of Information-Theoretic principles can contribute to explaining and understanding quantum phenomena, as well as to study their explanatory limitations. This is achieved in part by offering an account of the kind of explanation that axiomatic reconstructions of Quantum Theory provide, and re-evaluating the epistemic status of the program in light of this explanation. As illustrative case studies, I take Clifton's, Bub's and (...) Halvorson's characterization theorem and Popescu's and Rohrlich's toy models, and their explanatory contribution with respect to quantum nonlocality. On the one hand, I argue that ARQITs can aspire to provide genuine explanations of quantum nonlocality. On the other hand, I argue that such explanations cannot rule out a mechanical quantum theory. (shrink)

The terms “perspectivism” and “perspectivalism” have been the focus of an intense philosophical discussion with important repercussions for the debate about the role of mechanisms in scientific explanations. However, leading exponents of the new mechanistic philosophy have conceded more than was necessary to the radically subjectivistic perspectivalism, and fell into the opposite error, by retaining not negligible residues of objectivistic views about mechanisms. In order to remove this vacillation between the subjective-cultural and the objective-natural sides of mechanisms, we shall raise (...) the question about theory-ladenness over again and interpret it in its connection with the technical–experimental nature of scientific knowledge, as affirming the perspectival character of scientific knowledge: It is because of the character at once theory-laden and practice-laden, i.e. technique-laden, of our putting questions to nature that empirical reality must be investigated from particular perspectives: nature can be known scientifically only from a potentially infinite number of perspectives or theoretical points of view, concretely exemplified by mechanisms or experimental ‘machines’ that allow specific access to specific aspects of sensible reality. (shrink)

Contributing to the recent debate on whether or not explanations ought to be differentiated from arguments, this article argues that the distinction matters to science education. I articulate the distinction in terms of explanations and arguments having to meet different standards of adequacy. Standards of explanatory adequacy are important because they correspond to what counts as a good explanation in a science classroom, whereas a focus on evidence-based argumentation can obscure such standards of what makes an explanation explanatory. I provide (...) further reasons for the relevance of not conflating explanations with arguments (and having standards of explanatory adequacy in view). First, what guides the adoption of the particular standards of explanatory adequacy that are relevant in a scientific case is the explanatory aim pursued in this context. Apart from explanatory aims being an important aspect of the nature of science, including explanatory aims in classroom instruction also promotes students seeing explanations as more than facts, and engages them in developing explanations as responses to interesting explanatory problems. Second, it is of relevance to science curricula that science aims at intervening in natural processes, not only for technological applications, but also as part of experimental discovery. Not any argument enables intervention in nature, as successful intervention specifically presupposes causal explanations. Students can fruitfully explore in the classroom how an explanatory account suggests different options for intervention. (shrink)

The paper presents, and discusses, four candidate explanations of the structure, and construction, of the bees’ honeycomb. So far, philosophers have used one of these four explanations, based on the mathematical Honeycomb Conjecture, while the other three candidate explanations have been ignored. I use the four cases to resolve a dispute between Pincock and Baker about the Honeycomb Conjecture explanation. Finally, I find that the two explanations focusing on the construction mechanism are more promising than those focusing exclusively on the (...) resulting, optimal structure. The main reason for this is that optimal structures do not uniquely determine the relevant optimization leading to the optimal structure. (shrink)

A primary goal of quantum computer science is to find an explanation for the fact that quantum computers are more powerful than classical computers. In this paper I argue that to answer this question is to compare algorithmic processes of various kinds and to describe the possibility spaces associated with these processes. By doing this, we explain how it is possible for one process to outperform its rival. Further, in this and similar examples little is gained in subsequently asking a (...) how-actually question. Once one has explained how-possibly, there is little left to do. (shrink)

This paper examines the theoretical differences obtaining between a mechanist like Moore and a teleologist like Rychlak. It is shown that mechanistic formulations invariably reduce the account to material and efficient causation, whereas teleologists want to bring in formal-final cause descriptions as well. Mechanists frame their explanations in third-person terms whereas teleologists often seek a first-person formulation of behavior. Moore's references to "private events" are shown to be extraspectively understood. A major theme of this paper is that Skinner actually capitalized (...) on the intentional nature of human behavior, and that it would be fairly easy to reconceptualize his theory and its empirical support in teleological terms. Careful examination of both the contingency and the discriminative-stimulus constructs are made in support of this contention. (shrink)

As the literature on Critical Realism in the social sciences is growing, it is about time to analyse whether a new, acceptable standard for social scientific explanations is being introduced. In order to do so, I will discuss the work of Christopher Lloyd, who analysed contributions of social scientists that rely on (what he called) a structurist ontology and a structurist methodology, and advocated a third option in the methodological debate between individualism and holism. I will suggest modifications to three (...) points of Lloyd's analysis, without abandoning Lloyd's intuitions completely. Firstly, the intuitions of the structurist ontology can be made explicit in a different way, without loosing the individual-society dualism. Secondly, opting for a structurist ontology does not necessarily imply opting for a structurist methodology. Ontology and methodology are related, but not as strongly as Lloyd supposes. Thirdly, the idea of a complete explanation, present in the structurist methodology, confuses causation and explanation while denying the pragmatics of explanation. A broader spectrum of explanatory forms can be defended. Criticizing Lloyd on these three points will lead me to the defence of an explanatory pluralism, which I relate to a minimal ontology. The intention of this reconceptualisation of structurism (and related Critical Realist applications) is to broaden possible perspectives on the explanatory praxis of the social scientist, and to question the reunification of the social sciences. It will also stipulate which form of interdisciplinarity is preferable for the social sciences. (shrink)

I emphasize the difference between bioethics and sciences that are relevant to bioethics on the one hand and the lifeworld on the other hand, to which problems of bioethics apply. The difference between types of experience in the scientific realm and in the lifeworld is reflected by the different definitions of nature they tend to favor. Against this background, I will claim that the object domains of the natural and the artificial are indeed better separated in the context of everyday (...) perception than is commonly assumed in academic discourse. This capacity for differentiation in everyday contexts makes it possible to give weight to the positive connotations of naturalness used against technological interference in nature in the lifeworld discourse. I will start with some preliminary terminological and historical remarks. Then I will turn to possible scientific ways of separating the domains of the natural and the artificial. In everyday practice they usually can be neither reproduced nor understood. This situation has contributed to the need for an explanation of the moral appeal to naturalness that one encounters in the lifeworld. After a discussion of explanations that are given in the bioethical discourse, I will propose a lifeworld concept that allows for the use of a fundamental boundary between the natural and the artificial. (shrink)

(1988). Historical explanations in modern physics? The lesson of quantum mechanics. International Studies in the Philosophy of Science: Vol. 3, No. 1, pp. 68-79.

The purpose of this paper is to provide a systematic appraisal of the covering law and statistical relevance theories of statistical explanation advanced by Carl G. Hempel and by Wesley C. Salmon, respectively. The analysis is intended to show that the difference between these accounts is inprinciple analogous to the distinction between truth and confirmation, where Hempel's analysis applies to what is taken to be the case and Salmon's analysis applies to what is the case. Specifically, it is argued (a) (...) that statistical explanations exhibit the nomic expectability of their explanandum events, which in some cases may be strong but in other cases will not be; (b) that the statistical relevance criterion is more fundamental than the requirement of maximal specificity and should therefore displace it; and, (c) that if statistical explanations are to be envisioned as inductive arguments at all, then only in a qualified sense since, in particular, the requirement of high inductive probability between explanans and explanandum must be abandoned. (shrink)

Mechanisms have become much-discussed, yet there is still no consensus on how to characterise them. In this paper, we start with something everyone is agreed on – that mechanisms explain – and investigate what constraints this imposes on our metaphysics of mechanisms. We examine two widely shared premises about how to understand mechanistic explanation: (1) that mechanistic explanation offers a welcome alternative to traditional laws-based explanation and (2) that there are two senses of mechanistic explanation that we call ‘epistemic explanation’ (...) and ‘physical explanation’. We argue that mechanistic explanation requires that mechanisms are both real and local. We then go on to argue that real, local mechanisms require a broadly active metaphysics for mechanisms, such as a capacities metaphysics. (shrink)

Reductionism is a metaphysical thesis, a claim about explanations, and a research program. The metaphysical thesis reductionists advance (and antireductionists accept) is that all facts, including all biological facts, are fixed by the physical and chemical facts; there are no non-physical events, states, or processes, and so biological events, states and processes are “nothing but” physical ones. The research program can be framed as a methodological prescription which follows from the claim about explanations. Antireductionism does not dispute reductionism’s metaphysical claim, (...) but rejects the explanatory claim and so the methodological moral. To a first approximation what reductionists and antireductionists disagree about is whether explanations in functional biology can be or need to be explained by or completed or perhaps replaced by explanations in terms of molecular biology.i And this disagreement over the adequacy of explanations in functional biology drives a significant methodological disagreement with consequence for the research program of biology. (shrink)

The etiological account of teleological function is beset by several difficulties, which I propose to solve by grafting onto the etiological theory a subordinated goal-contribution clause. This approach enables us to ascribe neither too many teleofunctions nor too few; to give a unitary, one-clause analysis that works just as well for teleological functions derived from Darwinian evolution, as for those derived from human intention; and finally, to save the etiological theory from falsification, by explaining how, in spite of appearances, the (...) theory can allow for evolutionary function loss. (shrink)

Millikan’s (1984. Language, Thought, and Other Biological Categories: New Foundations for Realism. MIT Press) selected effects theory of functions states that functions are effects for which the ancestors of a trait were selected for. As the function is an effect a thing’s ancestors produced, only things that are reproductions in some sense can have functions. Against this reproduction requirement, Garson (2019. What Biological Functions Are and Why They Matter. Cambridge University Press) argues that not only processes of differential reproduction but (...) also processes of differential persistence can lead to new functions. Since such “persistence functions” have the same explanatory power as traditional selected effects functions, selected effects theorists should include them in their theory. In this paper, I will defend Millikan’s theory against this argument. I will show that the proponents of the generalized theory have yet to provide a working notion of populations that avoids a liberality problem. Further, I will argue that persistence functions are at best a marginal case of functions due to their restricted explanatory power. (shrink)

We characterize a type of functional explanation that addresses why a homologous trait originating deep in the evolutionary history of a group remains widespread and largely unchanged across the group’s lineages. We argue that biologists regularly provide this type of explanation when they attribute conserved functions to phenotypic and genetic traits. The concept of conserved function applies broadly to many biological domains, and we illustrate its importance using examples of molecular sequence alignments at the intersection of evolution and cell biology. (...) We use these examples to show how the study of conserved functions can integrate knowledge of a trait’s causal effects on fitness and its history of natural selection without invoking adaptation. We also show how conserved function provides a novel basis for addressing objections against evolutionary functions raised by Robert Cummins. (shrink)

The rise of mechanistic science in the seventeenth century helped give rise to a heated debate about whether teleology—the appearance of purposive activity in life and in mind—could be naturalized. At issue here were both what is meant by “teleology” as well as what is meant “nature”. I shall examine a specific episode in the history of this debate in the twentieth century with the rise of cybernetics: the science of seemingly “self-controlled” systems. Against cybernetics, Hans Jonas argued that cybernetics (...) failed as a naturalistic theory of teleology and that the reality of teleology is grounded in phenomenology, not in scientific explanations. I shall argue that Jonas was correct to criticize cybernetics but that contemporary work in biological organization succeeds where cybernetics failed. I will then turn to contemporary uses of Jonas’s phenomenology in enactivism and argue that Jonas’s phenomenology should be avoided by enactivism as a scientific research program, but that it remains open whether enactivism as a philosophy of nature should also avoid Jonas. (shrink)

Disputes about the causal structure of natural selection have implications for teleosemantics. Etiological, mainstream teleosemantics is based on a causalist view of natural selection. The core of its solution to Brentano’s Problem lies in the solution to Kant’s Puzzle provided by the Modern Synthesis concerning populational causation. In this paper, I suggest that if we adopt an alternative, statisticalist view on natural selection, the door is open for two reflections. First, it allows for setting different challenges to etiological teleosemantics that (...) arise if a statisticalist reading of natural selection is right. Second, by providing a different solution to Kant’s Puzzle based on individual causes of evolution, statisticalism promotes a different answer to Brentano’s Problem, what I label as Agential Teleosemantics. (shrink)

Amie Thomasson and other proponents of author-intention-based accounts of artifacts hold that an artifact is what its original author(s) intended it to be. By contrast, according to the user-based framework developed by Beth Preston, an artifact’s function is determined by the practices of users and reproducers. In this chapter, I argue that both author-intention-based and user-based frameworks suffer from an overly agent-centric orientation: despite their many interesting differences, both approaches run into difficulties with scenarios in which the attitudes or dispositions (...) of the relevant agents, whether they are authors, users or reproducers, do not serve as a reliable guide on which to base an artifact’s classification as a member of a certain artifact kind. Such alternative categorizations, which conflict with both author-intentions and user-practices, demonstrate the need for a more object-centered alternative perspective concerning prototype production and the nature of artifacts more generally. (shrink)

Assembly of minimal genomes revealed many genes encoding unknown functions. Three overlooked functional categories account for some of them. Cells are prone to make errors and age. As a first key function, discrimination between proper and changed entities is indispensable. Discrimination requires management of information, an authentic, yet abstract, cur- rency of reality. For example proteins age, sometimes very fast. The cell must identify, then get rid of old proteins without destroying young ones. Implementing discrimination in cells leads to the (...) second set of functions, usually ignored. Being abstract, information must nevertheless be embodied into material entities, with unavoidable idiosyncratic properties. This brings about novel unmet needs. Hence, the buildup of cells elicits specific but awkward material implementations, ‘kludges’ that become essential under particular settings, while difficult to identify. Finally, a third functional category char- acterizes the need for growth, with metabolic implementations allowing the cell to put together the growth of its cytoplasm, membranes, and genome, spanning different spatial dimensions. Solving this metabolic quandary, critical for engineering novel synthetic biology chassis, uncovered an unexpected role for CTP synthetase as the coordinator of nonhomothetic growth. Because a significant number of SynBio constructs aim at creating cell factories we expect that they will be attacked by viruses (it is not by chance that the function of the CRISPR system was identified in industrial settings). Substantiating the role of CTP, natural selection has dealt with this hurdle via synthesis of the antimetabolite 30-deoxy-30,40-didehydro- CTP, recruited for antiviral immunity in all domains of life. (shrink)

Central to vaccination-induced responses, antibodies are suggested by Vaz to operate as observer-dependent entities that owe their status to categorization schemes of immunologists. Inspired by color research by Maturana, he argues that antibodies should be distinguished from immunoglobulins, which unlike the former can be considered as constituents of structural dynamics of an organism, products of millions of years of evolution. However, a deeper understanding of the historical roots of the concept of immunoglobulin and associated “languaging” and naming processes reveals that (...) immunoglobulins, as much as antibodies, are contingent on conceptual schemes of immunology. (shrink)

I develop an account of ecological role functions—the functions of species within ecosystems—which is informed by alternative regime phenomena in ecology. My account is a causal-role theory which includes a counterfactual sensitivity condition. The account tracks and explains a distinction ecologists make between functions and various activities which are not functions. My counterfactual sensitivity condition resolves the liberality problem often attributed to causal-role theories of function, while also illuminating the explanatory centrality of role functions within ecology.

Donald Davidson’s causal theory of actions states that actions must be rationalized and caused by a belief-desire-pair. One problem of such a causal theory are cases of deviant causal chains. In these cases, the rationalized action is not caused in the right way but via a deviant causal chain. It therefore intuitively seems to be no action while all conditions of the causal theory are met. I argue that the problem of deviant causal chains can be solved by adding a (...) teleofunctionalist condition. This condition requires that the belief-desire pair that rationalizes an action must cause that action in a selection-historically normal way. I try to show that this additional condition drops counterintuitive cases of deviant causal chains out of the class of actions while being flexible enough to classify such cases as actions in which causal detours are intuitively permissible. (shrink)

The recent literature on causality has seen the introduction of several distinctions within causality, which are thought to be important for understanding the widespread scientific practice of focusing causal explanations on a subset of the factors that are causally relevant for a phenomenon. Concepts used to draw such distinctions include, among others, stability, specificity, proportionality, or actual-difference making. In this contribution, I propose a new distinction that picks out an explanatorily salient class of causes in biological systems. Some select causes (...) in complex biological systems, I argue, have the property of enabling coherent causal control of these systems. Examples of such control variables include hormones and other signaling molecules, e.g., TOR (target of rapamycin), morphogens or the products of homeotic selector genes in embryonic pattern formation. I propose an analysis of this notion based on concepts borrowed from causal graph theory. (shrink)

The theoretical biology movement originating in Britain in the early 1930’s and the biosemiotics movement which took off in Europe in the 1980’s have much in common. They are both committed to replacing the neo-Darwinian synthesis, and they have both invoked theories of signs to this end. Yet, while there has been some mutual appreciation and influence, particularly in the cases of Howard Pattee, René Thom, Kalevi Kull, Anton Markoš and Stuart Kauffman, for the most part, these movements have developed (...) independently of each other. Focussing on morphogenesis understood as vegetative semiosis, in this paper I will argue that the ideas of these movements are commensurate. Furthermore, synthesising them would enable us to see life processes as proto-narratives. Doing so will involve synthesising biohermeneutics, Peircian biosemiotics with Waddington’s theoretical biology and Piagetian genetic structuralism, and this, I claim, would strengthen the challenge of these traditions to mainstream biology. At the same time, this should contribute to overcoming the opposition between the sciences and the humanities, developing a broader tradition of Schellingian thought which involves developing the humanities and then demanding of the physical and biological sciences that they are consistent with and can make intelligible the emergence of humans as conceived by the humanities. (shrink)

The proper function of the heart is pumping the blood. According to what we call the type etiological view, this is because previous tokens of the type HEART were selected for pumping the blood. Nanay :412–431, 2010) argues that the type etiological view is viciously circular. He claims that the only plausible accounts of trait type individuation use proper functions, such that whenever the type etiological view is supplemented with a plausible account of trait type individuation, the result is a (...) view that uses proper functions to explain proper functions. We refine this objection, and argue that Nanay at most establishes a potentially benign definitional circularity. However, we show that the type etiological view’s reliance on types nevertheless generates a vicious regress. Hence the type etiological view is false. We reject dispositional and modal alternatives to the type etiological view for the reason that they either cannot accommodate malfunction, or do so at the cost of proliferation; and then formulate a novel token etiological view that overcomes both problems because it makes no reference to trait types. (shrink)